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Analgesic action of 3-hydroxy-N-methyl morphinan hydrobromide (dromoran).

作者信息

RANDALL L O, LEHMANN G

出版信息

J Pharmacol Exp Ther. 1950 Jun;99(2):163-70.

PMID:15437289
Abstract
摘要

相似文献

1
Analgesic action of 3-hydroxy-N-methyl morphinan hydrobromide (dromoran).
J Pharmacol Exp Ther. 1950 Jun;99(2):163-70.
2
The analgesic effect of dromoran hydrobromide (3-hydroxy-N-methyl morphinan hydrobromide) in postoperative pain.
N Engl J Med. 1951 Feb 22;244(8):286-8. doi: 10.1056/NEJM195102222440803.
3
Effectiveness of dromoran (3-hydroxyn-methyl morphinan) as an analgesic in thoracic surgery.
J Thorac Surg. 1950 Jul;20(1):90-6.
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[Clinical experiences with dromoran, (--3-oxy-N-methyl-morphinan tartrate, a new synthetic analgesic].[度冷丁（-3-氧代-N-甲基吗啡烷酒石酸盐，一种新型合成镇痛药）的临床经验]
Schweiz Med Wochenschr. 1951 Nov 3;81(44):1086-9.
5
[Inhibition of the antidiuretic effect of morphine and dromoran by 3-hydroxy-N-allyl-morphinan (levallorphan) in man].[3-羟基-N-烯丙基吗啡喃（烯丙左吗喃）对人体中吗啡和吗啉乙基吗啡抗利尿作用的抑制]
Klin Wochenschr. 1957 Sep 1;35(17):851-5. doi: 10.1007/BF01481470.
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Studies on the syntheses of hydrogenated quinolines and isoquinolines as analgesics, XV. Synthesis of 3-hydroxy-N-methyl-7-aza-des-N-morphinan (9-hydroxy-3-methyl-5, 10b-trimethylene-1,2,3,4,4a,4,6, 10b-octahydrobenzo(f)isoquinoline.氢化喹啉和异喹啉作为镇痛药的合成研究，XV。3-羟基-N-甲基-7-氮杂去-N-吗啡喃（9-羟基-3-甲基-5,10b-三亚甲基-1,2,3,4,4a,4,6,10b-八氢苯并(f)异喹啉）的合成。
Chem Pharm Bull (Tokyo). 1958 Aug;6(4):429-33. doi: 10.1248/cpb.6.429.
7
Studies on the syntheses of hydrogenated quinolines and isoquinolines as analgesics. XIII. Synthesis of 3-hydroxy-N-methyl-6-aza-des N-morphinan (N-methyl-9-hydroxy-5,10b-trimethylene-1,2,3,4,4a,5,6,10b-octahydrobenzo[h]isoquinoline.氢化喹啉和异喹啉作为镇痛药的合成研究。十三、3-羟基-N-甲基-6-氮杂去N-吗啡喃（N-甲基-9-羟基-5,10b-三亚甲基-1,2,3,4,4a,5,6,10b-八氢苯并[h]异喹啉）的合成。
Pharm Bull. 1957 Aug;5(4):316-9. doi: 10.1248/cpb1953.5.316.
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Synthesis in the morphinan group. I. Synthesis of C -nor and -homo derivatives of 3-hydroxy-N-methyl-morphinan.吗啡喃类化合物的合成。I. 3-羟基-N-甲基吗啡喃的C-去甲和高同系物衍生物的合成。
Pharm Bull. 1956 Aug;4(4):237-43.
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Studies on the syntheses of hydrogenated quinolines and isoquinolines as analgesics. VIII. Synthesis of N-methyl-16-aza-des-N-morphinan (N-methyl-4b, 9-methanoiminomethano-4b, 5, 6, 7, 8, 8a, 9, 10-octahydrophenanthrene).氢化喹啉和异喹啉作为镇痛药的合成研究。VIII. N-甲基-16-氮杂-去-N-吗啡喃（N-甲基-4b, 9-亚甲基亚氨基甲撑-4b, 5, 6, 7, 8, 8a, 9, 10-八氢菲）的合成
Pharm Bull. 1956 Oct;4(5):353-7. doi: 10.1248/cpb1953.4.353.
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Studies on the syntheses of hydrogenated quinolines and isoquinolines as analgesics. XII. Synthesis of N-methyl-7-aza-des-N-morphinan (3-methyl-5, 10b-trimethylene-1, 2, 3, 4, 4a, 5, 6, 10b-octahydrobenzo (f)isoquinoline).作为镇痛药的氢化喹啉和异喹啉的合成研究。十二、N-甲基-7-氮杂去-N-吗啡喃（3-甲基-5,10b-三亚甲基-1,2,3,4,4a,5,6,10b-八氢苯并(f)异喹啉）的合成
Pharm Bull. 1957 Feb;5(1):67-70. doi: 10.1248/cpb1953.5.67.

引用本文的文献

1
Levorphanol in the Perioperative Setting: Decreasing Opioid Requirements While Improving Pain Management.左旋吗啡在围手术期的应用：减少阿片类药物需求，同时改善疼痛管理。
J Pain Res. 2020 Oct 29;13:2721-2727. doi: 10.2147/JPR.S271456. eCollection 2020.
2
Synthetic substances with morphine-like effect: clinical experience; potency, side-effects, addiction liability.具有吗啡样作用的合成物质：临床经验；效能、副作用、成瘾倾向。
Bull World Health Organ. 1957;17(4-5):569-863.
3
Synthetic substances with morphine-like effect; relationship between chemical structure and analgesic action.
具有吗啡样作用的合成物质；化学结构与镇痛作用之间的关系。
Bull World Health Organ. 1955;13(6):937-98.
4
Peripheral effects of the optical antipodes of 3-hydroxy-n-methyl-morphinan and some of their derivatives.3-羟基-N-甲基吗啡喃及其某些衍生物的旋光对映体的外周效应。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;220(1-2):26-39. doi: 10.1007/BF00246091.
5
Analgesic and other properties of 3: 3-dithienylalkenylamines.3,3 - 二噻吩基链烯基胺的镇痛及其他特性
Br J Pharmacol Chemother. 1953 Mar;8(1):2-9. doi: 10.1111/j.1476-5381.1953.tb00739.x.
6
L-Methorphinan as a supplement to nitrous oxide and oxygen anaesthesia.左美沙芬作为氧化亚氮和氧气麻醉的补充剂。
Br Med J. 1952 Dec 20;2(4798):1331-3. doi: 10.1136/bmj.2.4798.1331.
7
Actions and uses of methorphinan.美沙芬的作用与用途。
Br Med J. 1952 Dec 20;2(4798):1328-30. doi: 10.1136/bmj.2.4798.1328.
8
Coupling of a new, active morphine derivative to sepharose for affinity chromatography.一种新型活性吗啡衍生物与琼脂糖偶联用于亲和色谱法。
Proc Natl Acad Sci U S A. 1972 Jul;69(7):1835-7. doi: 10.1073/pnas.69.7.1835.