Leake J F
Woman's Clinic, Sandusky, Ohio.
Curr Opin Obstet Gynecol. 1992 Feb;4(1):81-5.
In the past two decades increasing interest has been directed toward defining tumors of low malignant potential with regard to diagnosis, treatment, and biologic behavior. Three factors that appear to be of prognostic significance include stage, cellular DNA content, and residual disease. Patients with tumors of low malignant potential should undergo surgical staging and optimal cytoreductive surgery when technically feasible. Although adjuvant chemotherapy does not appear to be efficacious in patients with tumors of low malignant potential as a whole, there may be a small subset of patients with poor prognostic factors that would benefit from chemotherapy. Second-look laparotomy is not indicated in the management of this disease except in the research setting.
在过去二十年中，人们越来越关注低恶性潜能肿瘤在诊断、治疗和生物学行为方面的定义。三个似乎具有预后意义的因素包括分期、细胞DNA含量和残留病灶。低恶性潜能肿瘤患者在技术可行时应接受手术分期和最佳的肿瘤细胞减灭术。虽然辅助化疗对整体低恶性潜能肿瘤患者似乎无效，但可能有一小部分具有不良预后因素的患者会从化疗中获益。除研究情况外，二次剖腹探查术不用于本病的治疗。
