一个家系中血友病B与重度情感障碍的共分离。

Cosegregation of Christmas disease and major affective disorder in a pedigree.

作者信息

Gill M, Castle D, Duggan C

机构信息

Institute of Psychiatry, DeCrespigny Park, London.

出版信息

Br J Psychiatry. 1992 Jan;160:112-4. doi: 10.1192/bjp.160.1.112.

DOI:10.1192/bjp.160.1.112

PMID:1543989

Abstract

Three males with factor-IX deficiency (Christmas disease) in one pedigree all had severe affective disorder. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for major affective disorder is located on the X chromosome.

摘要

在一个家系中，三名患有因子IX缺乏症（克里斯马斯病）的男性均患有严重的情感障碍。这种明显的共分离现象（如果属实）将支持以下假说：在某些家系中，一种导致严重情感障碍的基因位于X染色体上。