Gill M, Castle D, Duggan C
Institute of Psychiatry, DeCrespigny Park, London.
Br J Psychiatry. 1992 Jan;160:112-4. doi: 10.1192/bjp.160.1.112.
Three males with factor-IX deficiency (Christmas disease) in one pedigree all had severe affective disorder. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for major affective disorder is located on the X chromosome.