Chapnick P, Diamond L H
Mount Sinai Hospital, Toronto, Ont.
J Can Dent Assoc. 1992 Jan;58(1):43-52.
This double blind clinical study was undertaken to evaluate the effectiveness of locally applied clindamycin in Gelfoam in reducing the incidence of dry socket formation after third molar surgery. A total of 1,021 third molar extractions were performed, and 520 mandibular third molar extractions of varied surgical difficulty were evaluated. The results indicated that this technique was effective. This study also demonstrates that the incidence of dry socket after third molar surgery is significantly higher in the mandible than the maxilla, in smokers than in non-smokers, and in females currently on oral contraceptives.
本双盲临床研究旨在评估局部应用于明胶海绵中的克林霉素在降低第三磨牙手术后干槽症发生率方面的有效性。总共进行了1021例第三磨牙拔除术，并对520例手术难度各异的下颌第三磨牙拔除术进行了评估。结果表明该技术有效。本研究还表明，第三磨牙手术后干槽症的发生率在下颌明显高于上颌，在吸烟者中高于非吸烟者，在目前正在服用口服避孕药的女性中也较高。
