Gilmore N J, Beaulieu R, Steben M, Laverdière M
CMAJ. 1992 Feb 1;146(3):371-5.
Acquired immunodeficiency syndrome, or AIDS, is a new illness that occurs in previously healthy individuals. It is characterized by immunodeficiency, opportunistic infections and unusual malignant diseases. Life-threatening single or multiple infections with viruses, mycobacteria, fungi or protozoa are common. A rare neoplasm, Kaposi's sarcoma, has developed in approximately one third of patients with AIDS. More than 800 cases of AIDS have been reported in North America, over 24 of them in Canada. The majority of patients are male homosexuals, although AIDS has also developed in abusers of intravenously administered drugs, Haitian immigrants, individuals with hemophilia, recipients of blood transfusions, prostitutes, and infants, spouses and partners of patients with AIDS. The cause of AIDS is unknown, but the features are consistent with an infectious process. Early diagnosis can be difficult owing to the nonspecific symptoms and signs of the infections and malignant diseases. Therefore, vigilance by physicians is of the utmost importance.
获得性免疫缺陷综合征,即艾滋病,是一种出现在先前健康个体身上的新疾病。其特征为免疫缺陷、机会性感染和罕见的恶性疾病。由病毒、分枝杆菌、真菌或原生动物引起的危及生命的单一或多重感染很常见。一种罕见的肿瘤,卡波西肉瘤,在约三分之一的艾滋病患者中出现。北美已报告800多例艾滋病病例,其中加拿大有24例以上。大多数患者是男性同性恋者,不过艾滋病也在静脉注射毒品滥用者、海地移民、血友病患者、输血接受者、妓女以及艾滋病患者的婴儿、配偶和伴侣中出现。艾滋病的病因不明,但症状符合感染过程。由于感染和恶性疾病的症状和体征不具特异性,早期诊断可能困难。因此,医生保持警惕至关重要。