Loop F D, Irarrazaval M J, Bredee J J, Siegel W, Taylor P C, Sheldon W C
Am J Cardiol. 1977 Apr;39(4):516-22. doi: 10.1016/s0002-9149(77)80160-4.
Four hundred consecutive patients, 80 percent of whom had multiple vessel obstruction, received a single internal mammary artery graft (121 patients) alone or combined with vein grafts (279 patients) in 1971 and 1972. Four patients died during or within 30 days of the operation. Sixteen patients had intraoperative infarction; three died. Arteriography was performed postoperatively (mean 12 months) in 254 patients, and 248 of 261 internal mammary artery grafts (95 percent) and 195 of 237 vein grafts (82 percent) were patent. Follow-up was complete (mean interval 38 months); all 80 patients with single vessel disease are alive, and the 3 year survival rate for patients with double and triple vessel disease was 98.7 and 94.4 percent, respectively. Comparison of longevity of 741 patients who had received vein grafts in 1967 to 1970 with that of 400 patients with internal mammary artery grafts (1971 to 1972) indicates greater survival for the recent series (P less than 0.004). Factors responsible for improved survival include (1) reduced operative mortality, (2) fewer intraoperative infarctions, (3) more complete revascularization, and (4) higher patency rate of the internal mammary artery graft.
1971年和1972年，400例连续患者接受了单支内乳动脉搭桥术（121例患者），单独使用或与静脉搭桥联合使用（279例患者），其中80%的患者存在多支血管阻塞。4例患者在手术期间或术后30天内死亡。16例患者发生术中梗死，3例死亡。254例患者术后（平均12个月）进行了血管造影，261支内乳动脉搭桥中有248支（95%）和237支静脉搭桥中有195支（82%）通畅。随访完整（平均间隔38个月）；所有80例单支血管病变患者均存活，双支和三支血管病变患者的3年生存率分别为98.7%和94.4%。将1967年至1970年接受静脉搭桥的741例患者的寿命与400例接受内乳动脉搭桥的患者（1971年至1972年）进行比较，结果显示近期系列患者的生存率更高（P<0.004）。生存率提高的因素包括：（1）手术死亡率降低；（2）术中梗死减少；（3）血管重建更完整；（4）内乳动脉搭桥的通畅率更高。
