功能基因组学的前景：完善细胞百科全书。

The promise of functional genomics: completing the encyclopedia of a cell.

作者信息

Hughes Timothy R, Robinson Mark D, Mitsakakis Nicholas, Johnston Mark

机构信息

Banting and Best Department of Medical Research, University of Toronto, 112 College St., Room 307, Toronto, ON, M5G 1L6, Canada.

出版信息

Curr Opin Microbiol. 2004 Oct;7(5):546-54. doi: 10.1016/j.mib.2004.08.015.

DOI:10.1016/j.mib.2004.08.015

PMID:15451511

Abstract

Genome sequencing provides complete parts lists of organisms. This presents the obvious challenge of determining how each gene contributes to the life of the organism. This task seems increasingly feasible; however, progress to date suggests that increased interaction between systematic efforts and individual investigators will be critical to completing the encyclopedia of the yeast cell.

摘要

基因组测序提供了生物体完整的部件清单。这带来了确定每个基因如何对生物体的生命活动产生影响这一显而易见的挑战。这项任务似乎越来越可行；然而，迄今为止的进展表明，系统研究与个体研究者之间加强互动对于完成酵母细胞百科全书至关重要。