迷走神经刺激术对癫痫患者的疗效：一项为期12年的观察

Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation.

作者信息

Uthman B M, Reichl A M, Dean J C, Eisenschenk S, Gilmore R, Reid S, Roper S N, Wilder B J

机构信息

Neurology Service, Malcom Randall Department of Veterans Affairs Medical Center, University of Florida College of Medicine and McKnight Brain Institute, Gainesville 32608, USA.

出版信息

Neurology. 2004 Sep 28;63(6):1124-6. doi: 10.1212/01.wnl.0000138499.87068.c0.

DOI:10.1212/01.wnl.0000138499.87068.c0

PMID:15452317

Abstract

A retrospective review of the safety, tolerability, and efficacy of vagus nerve stimulation (VNS) in 48 patients with intractable partial epilepsy was performed. Side effects were few and mild to moderate. Mean seizure frequency decreased by 26% after 1 year, 30% after 5 years, and 52% after 12 years with VNS treatment.

摘要

对48例顽固性部分性癫痫患者迷走神经刺激（VNS）的安全性、耐受性和疗效进行了回顾性研究。副作用少，且为轻至中度。接受VNS治疗后，1年时平均癫痫发作频率降低26%，5年时降低30%，12年时降低52%。