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牛乳蛋白质命名法——第六版修订本

Nomenclature of the proteins of cows' milk--sixth revision.

作者信息

Farrell H M, Jimenez-Flores R, Bleck G T, Brown E M, Butler J E, Creamer L K, Hicks C L, Hollar C M, Ng-Kwai-Hang K F, Swaisgood H E

机构信息

US Department of Agriculture, Eastern Regional Research Center, Wyndmoor, PA 19038, USA.

出版信息

J Dairy Sci. 2004 Jun;87(6):1641-74. doi: 10.3168/jds.S0022-0302(04)73319-6.

Abstract

This report of the American Dairy Science Association Committee on the Nomenclature, Classification, and Methodology of Milk Proteins reviews changes in the nomenclature of milk proteins necessitated by recent advances of our knowledge of milk proteins. Identification of major caseins and whey proteins continues to be based upon their primary structures. Nomenclature of the immunoglobulins consistent with new international standards has been developed, and all bovine immunoglobulins have been characterized at the molecular level. Other significant findings related to nomenclature and protein methodology are elucidation of several new genetic variants of the major milk proteins, establishment by sequencing techniques and sequence alignment of the bovine caseins and whey proteins as the reference point for the nomenclature of all homologous milk proteins, completion of crystallographic studies for major whey proteins, and advances in the study of lactoferrin, allowing it to be added to the list of fully characterized milk proteins.

摘要

美国乳业科学协会乳蛋白命名、分类及方法委员会的这份报告回顾了由于我们对乳蛋白知识的最新进展而导致的乳蛋白命名变化。主要酪蛋白和乳清蛋白的鉴定仍然基于它们的一级结构。已经制定了符合新国际标准的免疫球蛋白命名法,并且所有牛免疫球蛋白都已在分子水平上进行了表征。与命名法和蛋白质方法相关的其他重要发现包括阐明了几种主要乳蛋白的新遗传变体,通过测序技术和序列比对确定牛酪蛋白和乳清蛋白作为所有同源乳蛋白命名的参考点,完成了主要乳清蛋白的晶体学研究,以及乳铁蛋白研究的进展,使其能够被添加到已完全表征的乳蛋白列表中。

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