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在有机催化的黄金时代。

In the golden age of organocatalysis.

作者信息

Dalko Peter I, Moisan Lionel

机构信息

Laboratoire de Recherches Organiques associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France.

出版信息

Angew Chem Int Ed Engl. 2004 Oct 4;43(39):5138-75. doi: 10.1002/anie.200400650.

Abstract

The term "organocatalysis" describes the acceleration of chemical reactions through the addition of a substoichiometric quantity of an organic compound. The interest in this field has increased spectacularly in the last few years as result of both the novelty of the concept and, more importantly, the fact that the efficiency and selectivity of many organocatalytic reactions meet the standards of established organic reactions. Organocatalytic reactions are becoming powerful tools in the construction of complex molecular skeletons. The diverse examples show that in recent years organocatalysis has developed within organic chemistry into its own subdiscipline, whose "Golden Age" has already dawned.

摘要

“有机催化”一词描述了通过添加亚化学计量的有机化合物来加速化学反应的过程。由于该概念的新颖性,更重要的是,许多有机催化反应的效率和选择性达到了既定有机反应的标准,在过去几年中,该领域的关注度急剧上升。有机催化反应正成为构建复杂分子骨架的有力工具。各种实例表明,近年来有机催化在有机化学领域已发展成为一门独立的子学科,其“黄金时代”已然来临。

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