膜性肾小球肾炎与克罗恩病之间的关联

[Association between membranous glomerulonephritis and Crohn's disease].

作者信息

Díaz Rodríguez C, Granja E, Vázquez Martul E, Sacristán F, Moreno Fernández A, González Rivero C, del Río Romero D, Trinidad J C

机构信息

Servicio de Nefrología, F. P. Hospital "Virxe da Xunqueira", Cée Coruña.

出版信息

Nefrologia. 2004;24(4):368-71.

PMID:15455498

Abstract

We report the case of a 37 year old man who suffered from Crohn's Disease (CD), and was receiving treatment with mesalazine (5-ASA). Nine years after the diagnosis, because of detecting a slight proteinuria, a renal biopsy is made, being the anatomo-pathologic result compatible with membranous glomerulonephritis (MGN). Checking previous literature we have only found two cases reported of MGN in coincidence with Inflammatory Bowel Disease (IBD), one in association with Ulcerative Colitis and the other with Crohn's Disease in a 12 years old boy. This is, therefore, the second case presenting MGN associated with CD and the first in an adult patient.

摘要

我们报告了一名37岁男性患者的病例，该患者患有克罗恩病（CD），正在接受美沙拉嗪（5-ASA）治疗。诊断9年后，由于检测到轻度蛋白尿，进行了肾活检，解剖病理学结果与膜性肾小球肾炎（MGN）相符。查阅既往文献，我们仅发现两例MGN与炎症性肠病（IBD）同时存在的病例报告，一例与溃疡性结肠炎相关，另一例与一名12岁男孩的克罗恩病相关。因此，这是第二例呈现MGN与CD相关的病例，也是首例成年患者。