Komu M
Department of Diagnostic Radiology, University of Turku, Finland.
Magn Reson Imaging. 1992;10(1):35-40. doi: 10.1016/0730-725x(92)90370-f.
The human calf muscle was examined by using the magnetization transfer MR imaging technique. The time-dependent saturation transfer (TDST) method was applied at low magnetic field 0.1 T in order to measure the mobile water relaxation time T1w, the magnetization transfer rate Rwm from water to solid macromolecules, and the magnetization transfer contrast (MTC) of the human tissue. The magnetization transfer contrast of 0.67 was attained. The transfer rate Rwm was 4.5 sec-1 (+/- 0.3 sec-1) for the anterior tibial muscle and 5.0 sec-1 (+/- 0.4 sec-1) for the gastrocnemius muscles. The values of Rwm are considerably larger than the values of corresponding relaxation rates measured at high fields. The relaxation rate measurements of human tissues in vivo was shown to be possible at 0.1 T even within the framework of normal routine MR imaging. Magnetization transfer MR imaging is a very promising and practical method in order to assess the relaxation processes in heterogeneous human tissues in vivo, and it can improve the tissue characterization possibilities of MR imaging techniques.
采用磁化传递磁共振成像技术对人体小腿肌肉进行了检查。为了测量人体组织中流动水的弛豫时间T1w、从水到固体大分子的磁化传递率Rwm以及磁化传递对比度（MTC），在0.1T的低磁场下应用了随时间变化的饱和传递（TDST）方法。获得了0.67的磁化传递对比度。胫骨前肌的传递率Rwm为4.5秒-1（±0.3秒-1），腓肠肌的传递率Rwm为5.0秒-1（±0.4秒-1）。Rwm的值明显大于在高磁场下测量的相应弛豫率的值。结果表明，即使在正常常规磁共振成像的框架内，在0.1T时也能够对人体组织进行体内弛豫率测量。磁化传递磁共振成像对于评估体内异质人体组织中的弛豫过程是一种非常有前景且实用的方法，并且它可以提高磁共振成像技术的组织特征描述能力。
