Barnetson R S, White A D
Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW.
Med J Aust. 1992 Mar 16;156(6):428-31. doi: 10.5694/j.1326-5377.1992.tb139850.x.
To discuss the various uses of corticosteroids in patients with skin diseases.
All relevant literature published since 1950 was reviewed and 33 studies were selected.
Systemic and topical corticosteroid preparations are used commonly in patients with skin diseases. Oral administration of steroids is particularly useful in acute hypersensitivity diseases, connective tissue diseases, immunological blistering diseases, and the commoner dermatoses when they are very severe and widespread. Topical steroid preparations are mainly used in the different forms of dermatitis, but are also useful in psoriasis and a number of other skin diseases. If potent topical steroid preparations are used for too long, or in excessive quantities, side effects will be encountered as a direct effect on the skin, for example atrophy, and as a result of systemic absorption, for example, hypothalamic-pituitary-adrenal suppression and Cushing's syndrome.
探讨皮质类固醇在皮肤病患者中的多种用途。
回顾了自1950年以来发表的所有相关文献，并选取了33项研究。
系统性和局部用皮质类固醇制剂在皮肤病患者中普遍使用。口服类固醇在急性超敏反应性疾病、结缔组织疾病、免疫性水疱病以及病情非常严重且广泛的常见皮肤病中特别有用。局部用类固醇制剂主要用于不同类型的皮炎，但对银屑病和其他一些皮肤病也有效。如果长期大量使用强效局部用类固醇制剂，会出现对皮肤的直接副作用，如萎缩，以及全身吸收导致的副作用，如下丘脑-垂体-肾上腺抑制和库欣综合征。
