Prawer S E, Katz H I
University of Minnesota Medical School, Minneapolis.
Am Fam Physician. 1990 May;41(5):1531-8.
Superpotent topical steroids used to treat psoriasis and steroid-responsive dermatoses may produce local cutaneous side effects, including atrophy, steroid acne, perioral dermatitis, hypopigmentation, hypertrichosis and superinfections. Suppression of the hypothalamic-pituitary-adrenal axis may be one of the systemic side effects. Superpotent topical steroids should not be used under occlusion, in flexural areas, on the face and in children. The total amount used per week and the duration of treatment should be carefully monitored.
用于治疗银屑病和类固醇反应性皮肤病的超强效局部用类固醇可能会产生局部皮肤副作用，包括萎缩、类固醇性痤疮、口周皮炎、色素减退、多毛症和二重感染。下丘脑-垂体-肾上腺轴的抑制可能是全身副作用之一。超强效局部用类固醇不应在封闭性敷料下使用、不应用于屈侧部位、面部和儿童。应仔细监测每周的使用总量和治疗持续时间。
