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CS - 1170在小儿感染中的应用结果(作者译)

[Results of application of CS-1170 to pediatric infections (author's transl)].

作者信息

Sohgen S, Yanagisawa K, Ichihashi H

出版信息

Jpn J Antibiot. 1979 Jan;32(1):25-8.

PMID:154583
Abstract

CS-1170 was administered in a total of 11 cases including respiratory infections, urinary-tract infections, and subacute bacterial endocarditis. It was effective in all of the cases; markedly effective in a case of bronchopneumonia with underlying Down's syndrome and infantile spasm and in 2 cases of urinary-tract infections with E. coli. The fact that it was effective for urinary-tract infection with E. coli which showed no sensitivity to ampicillin or cefazolin demonstrates the clinical significance and usefulness of CS-1170 which is said to have a strong antibacterial activity for bacterial producing beta-lactamase. No side effect was observed.

摘要

CS - 1170应用于总共11例患者,包括呼吸道感染、尿路感染和亚急性细菌性心内膜炎。所有病例均有效;对1例合并唐氏综合征及婴儿痉挛症的支气管肺炎以及2例大肠杆菌引起的尿路感染疗效显著。CS - 1170对氨苄西林或头孢唑林不敏感的大肠杆菌引起的尿路感染有效,这一事实证明了CS - 1170的临床意义和实用性,据说它对产生β - 内酰胺酶的细菌具有强大的抗菌活性。未观察到副作用。

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