Palmer Mitchell V, Carpenter Jeremy G
Bacterial Diseases of Livestock Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA.
J Vet Diagn Invest. 2004 Sep;16(5):475-7. doi: 10.1177/104063870401600522.
Polycystic kidney and liver disease was seen in a stillborn white-tailed deer (Odocoileus virginianus) fawn. Bilaterally enlarged kidneys were characterized by severe dilatation of all renal tubules. Glomeruli were sparse, small, and located within a dilated Bowman's capsule. The liver was characterized by marked periportal fibrosis, biliary hyperplasia, and bile duct ectasia with dilated ducts containing inspissated bile. The presentation and morphology of this case are most similar to autosomal recessive polycystic disease in humans.
在一只死产的白尾鹿(弗吉尼亚鹿)幼崽中发现了多囊肾和多囊肝病。双侧肿大的肾脏表现为所有肾小管严重扩张。肾小球稀疏、细小,位于扩张的鲍曼囊中。肝脏的特征是明显的门周纤维化、胆管增生以及胆管扩张,扩张的胆管内含有浓缩胆汁。该病例的表现和形态与人类常染色体隐性多囊病最为相似。