Brombacher-Frey I, Wöckel W, Kreusser T
Pneumologische Klinik, Zentralkrankenhauses Gauting, LVA Obb.
Pneumologie. 1992 Jan;46(1):12-9.
We report on 4 thoracic actinomycoses; in three of these four cases a bronchial carcinoma was suspected, and in case No. 2 this carcinoma had been considered to be in a very advanced and inoperable stage. A man of 51 years of age was in a generally run-down condition. He also noticed that his sputum was tinged with blood. The x-ray film showed a large space-occupying growth at the right lung hilus. Repeated perbronchial biopsies of the focus did not yield any diagnosis. Actinomycosis was identified histologically only in the tissue samples obtained via thoracotomy. After a three-month penicillin course the hilar shadow receded. A 61-year old male patient was transferred to our Pneumological Hospital, being strongly suspected of suffering from an extensive bronchial carcinoma, and having multiple intrathoracic space-occupying growths as well as pleural effusions, a pericardial effusion, and an infiltration of the left thoracic wall with fistula formation; however, histological examination of skin biopsies revealed that he was suffering from actinomycosis. Antibiotic therapy cured him completely in a six-month course. In a man of 32 years of age who had been indulging for many years in a severe abuse of nicotin, we suspected a central bronchial carcinoma on the basis of his x-ray, but histology of the tissue taken from the space-occupying growth via diagnostic thoracotomy revealed that this patient, too, suffered from actinomycosis. Complete recession occurred after several months of antibiotic treatment. A woman of 82 years had been an inpatient for several months in another hospital because of relapsing pleuropneumonias on the right side. She was transferred to us as an outpatient after a renewed relapse. We conducted a transcutaneous fine-needle biopsy of the right indurating pleural effusion. A few actinomyces filaments were seen on histological examination of the purulent exudate. Hence, actinomycosis was confirmed. After antibiotic therapy the finding receded completely.
我们报告了4例胸段放线菌病;在这4例中的3例中,怀疑患有支气管癌,在第2例中,该癌被认为处于非常晚期且无法手术的阶段。一名51岁的男子身体普遍衰弱。他还注意到痰中带血。X线片显示右肺门有一个大的占位性病变。对病灶反复进行支气管周围活检未得出任何诊断结果。仅在通过开胸手术获取的组织样本中经组织学检查确诊为放线菌病。经过三个月的青霉素疗程,肺门阴影消退。一名61岁的男性患者被转至我们的肺病医院,强烈怀疑患有广泛的支气管癌,有多个胸腔内占位性病变以及胸腔积液、心包积液,左侧胸壁有浸润并形成瘘管;然而,皮肤活检的组织学检查显示他患有放线菌病。抗生素治疗在六个月的疗程后使他完全康复。一名32岁的男子多年来严重滥用尼古丁,根据其X线表现怀疑患有中央型支气管癌,但通过诊断性开胸手术从占位性病变获取的组织的组织学检查显示,该患者也患有放线菌病。经过几个月的抗生素治疗后完全消退。一名82岁的女性因右侧复发性胸膜炎性肺炎在另一家医院住院数月。再次复发后作为门诊患者转至我们医院。我们对右侧硬结性胸腔积液进行了经皮细针活检。在脓性渗出物的组织学检查中发现了一些放线菌细丝。因此,确诊为放线菌病。抗生素治疗后该病症完全消退。