Commun Dis Intell Q Rep. 2004;28(2):187-93. doi: 10.33321/cdi.2004.28.16.
The Australian Gonococcal Surveillance Programme monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all Australian states and territories. In 2003 the in vitro susceptibility of 3,772 isolates of gonococci from public and private sector sources was determined by standardised methods. Antibiotic susceptibility patterns again varied considerably between jurisdictions and regions. Resistance to the penicillins nationally, was 17 per cent but ranged up to 27 per cent in larger urban centres. Quinolone resistance in gonococci (QRNG) remained widespread and increased in most states but most markedly in Victoria. Nationally, 14.4 per cent of all isolates were QRNG, and most of this resistance was at high MIC levels. All isolates remained sensitive to spectinomycin. A small number of isolates showed some decreased susceptibility to ceftriaxone (MIC 0.06 mg/L or more) and were concentrated in New South Wales. A high proportion of gonococci examined in larger urban centres were from male patients and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract. In New South Wales, the number of available cultures decreased and represented 30 per cent of the national total. In Victoria, the number of isolates increased and was 25 per cent of all gonococci examined.
澳大利亚淋病监测项目对在澳大利亚所有州和领地分离出的淋病奈瑟菌的抗生素敏感性进行监测。2003年，采用标准化方法测定了来自公共和私营部门的3772株淋病奈瑟菌的体外敏感性。不同司法管辖区和地区之间的抗生素敏感性模式再次存在很大差异。全国范围内对青霉素的耐药率为17%，但在较大的城市中心高达27%。淋病奈瑟菌喹诺酮耐药性（QRNG）仍然普遍存在，大多数州有所增加，但在维多利亚州最为明显。全国范围内，所有分离株中有14.4%为QRNG，且大多数耐药性处于高最低抑菌浓度水平。所有分离株对壮观霉素仍敏感。少数分离株对头孢曲松的敏感性有所下降（最低抑菌浓度为0.06mg/L或更高），且集中在新南威尔士州。在较大城市中心检测的淋病奈瑟菌中，很大一部分来自男性患者，直肠和咽部分离株很常见。在其他中心以及澳大利亚农村地区，病例的男女比例较低，且大多数分离株来自生殖道。在新南威尔士州，可用培养物数量减少，占全国总数的30%。在维多利亚州，分离株数量增加，占所有检测淋病奈瑟菌的25%。
