Commun Dis Intell Q Rep. 2007 Jun;31(2):180-4. doi: 10.33321/cdi.2007.31.13.
The Australian Gonococcal Surveillance Programme (AGSP) monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all states and territories. In 2006 the in vitro susceptibility of 3,850 isolates of gonococci from public and private sector sources was determined by standardised methods. Different antibiotic susceptibility patterns were again seen in the various jurisdictions and regions. Resistance to the penicillins nationally was at 34% and, with the exception of the Northern Territory, ranged between 17% and 51%. Quinolone resistance in gonococci increased, especially in Queensland, with resistance to this agent found in all jurisdictions. Nationally, 38% of all isolates were ciprofloxacin-resistant, and most of this resistance was at high minimum inhibitory concentration (MIC) levels. With the exception of the Northern Territory excepted, proportions of quinolone resistant gonococci ranged between 16% and 54%. All isolates remained sensitive to spectinomycin. Less than 1% of isolates showed some decreased susceptibility to ceftriaxone. A high proportion of gonococci examined in larger urban centres were from male patients and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract.
澳大利亚淋病监测项目（AGSP）监测在所有州和领地分离出的淋病奈瑟菌的抗生素敏感性。2006年，采用标准化方法测定了来自公共和私营部门的3850株淋病奈瑟菌的体外敏感性。在各个司法管辖区和地区再次观察到不同的抗生素敏感性模式。全国范围内对青霉素的耐药率为34%，除北领地外，耐药率在17%至51%之间。淋病奈瑟菌对喹诺酮类药物的耐药性增加，尤其是在昆士兰州，所有司法管辖区均发现了对该药物的耐药性。在全国范围内，所有分离株中有38%对环丙沙星耐药，且大多数耐药性处于高最低抑菌浓度（MIC）水平。除北领地外，喹诺酮耐药淋病奈瑟菌的比例在16%至54%之间。所有分离株对壮观霉素仍敏感。不到1%的分离株对头孢曲松的敏感性有所下降。在较大城市中心检测的淋病奈瑟菌中，很大一部分来自男性患者，直肠和咽部分离株很常见。在其他中心以及澳大利亚农村地区，病例的男女比例较低，且大多数分离株来自生殖道。
