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情感障碍的心理神经内分泌学:综述

Psychoneuroendocrinology of affective disorder: an overview.

作者信息

Ettigi P G, Brown G M

出版信息

Am J Psychiatry. 1977 May;134(5):493-501. doi: 10.1176/ajp.134.5.493.

DOI:10.1176/ajp.134.5.493
PMID:15462
Abstract

Neuroendocrine function has been reported by several workers to be abnormal in affective disorder. It has been shown that neurotransmitters (noradrenaline, dopamine, and serotinin) are involved in the regulation of neuroendocrine function. Several biological hypotheses of affective disorder have implicated a defect in neurotransmitter function, but these hypotheses have been found lacking in part over the years. The study of neuroendocrine abnormalities found in various types of affective disorder may clarify some aspects of this complex issue by reflecting neurotransmitter activity in this disorder. Such studies should help further explain affective illness.

摘要

几位研究人员报告称,情感障碍患者的神经内分泌功能存在异常。研究表明,神经递质(去甲肾上腺素、多巴胺和血清素)参与神经内分泌功能的调节。情感障碍的几种生物学假说都涉及神经递质功能缺陷,但多年来发现这些假说部分存在不足。对各类情感障碍中发现的神经内分泌异常进行研究,可能通过反映该疾病中的神经递质活性,来阐明这一复杂问题的某些方面。此类研究应有助于进一步解释情感性疾病。

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