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补体与寄生吸虫

Complement and parasitic trematodes.

作者信息

Fishelson Z

机构信息

Department of Chemical Immunology, The Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel.

出版信息

Parasitol Today. 1989 Jan;5(1):19-25. doi: 10.1016/0169-4758(89)90218-4.

Abstract

The complement (C) system acts as a barrier to protect our bodies against invading pathogens. It may react to cytophilic antibodies or directly to foreign molecules presented by the intruder. As well as their cytotoxic activity, C components can attract and attach leucocytes to the surface of the foreign body, and activate them to kill it. Zvi Fishelson describes various strategies used by a parasitic trematode to escape immune damage in the face of potent immune surveillance by C and other effector mechanisms.

摘要

补体(C)系统作为一种屏障,保护我们的身体免受入侵病原体的侵害。它可能对嗜细胞抗体作出反应,或直接对入侵者呈现的外来分子作出反应。除了其细胞毒性活性外,补体成分还可以吸引白细胞并使其附着在异物表面,并激活它们来杀死异物。兹维·费舍尔森描述了一种寄生吸虫面对补体和其他效应机制的强大免疫监视时,为逃避免疫损伤而采用的各种策略。

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