Kittl E M, Diridl G, Lenhart V, Neuwald C, Tomasits J, Pichler H, Bauer K
Zentrallabor, Franz-Josef-Spitals, Wien.
Wien Klin Wochenschr. 1992;104(1):21-4.
In patients with malaria the lipid parameters triglycerides, cholesterol, and HDL-cholesterol were determined routinely. At the time of admission hypertriglyceridemia, hypocholesterolemia, and an extreme decrease in HDL-cholesterol were found. This dyslipoproteinemia was present in cases of falciparum malaria, as well as in cases of benign tertian malaria. The extent of HDL-cholesterol decrease showed no correlation to the severity of the clinical course of disease. HDL-cholesterol has proven to be an independent diagnostic laboratory finding in cases of suspected malarial infection. This parameter displays high diagnostic sensitivity, but no specificity for malaria.
对疟疾患者常规测定血脂参数甘油三酯、胆固醇和高密度脂蛋白胆固醇。入院时发现有高甘油三酯血症、低胆固醇血症以及高密度脂蛋白胆固醇极度降低的情况。这种血脂蛋白异常在恶性疟病例以及良性间日疟病例中均有出现。高密度脂蛋白胆固醇降低的程度与疾病临床病程的严重程度无相关性。在疑似疟疾感染的病例中，高密度脂蛋白胆固醇已被证明是一项独立的诊断实验室指标。该指标显示出较高的诊断敏感性，但对疟疾无特异性。
