Colosimo C, Lebon P, Martelli M, Tumminelli F, Mandelli F
International Medical Service, Roma, Italy.
Acta Neurol Belg. 1992;92(1):24-9.
Probable progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of clinical picture and magnetic resonance imaging in a 63-year-old man with a complete remission of a non-Hodgkin's lymphoma. After the introduction of intramuscular alpha-interferon therapy, his neurological state and MRI findings showed a clear improvement. Eighteen months after the onset of first symptoms the patient has significantly recovered from both aphasia and motor impairment, and shows only a mild attentional deficit.
一名63岁非霍奇金淋巴瘤完全缓解的男性患者，根据临床表现和磁共振成像诊断为可能的进行性多灶性白质脑病（PML）。在开始肌内注射α-干扰素治疗后，他的神经状态和MRI表现明显改善。首次出现症状18个月后，患者的失语和运动障碍已显著恢复，仅表现出轻度注意力缺陷。
