Sun Z, Zheng H
School of Applied Medical Sciences and Sports Studies, University of Ulster, Newtownabbey, Northern Ireland, UK.
Eur J Vasc Endovasc Surg. 2004 Nov;28(5):534-42. doi: 10.1016/j.ejvs.2004.08.005.
The behaviour of stent struts crossing the renal ostia and their effect on renal ostia configuration is not well understood. The study aims to investigate whether suprarenal stent struts affect the morphological change of the renal artery with ostial calcification observed on CT virtual intravascular endoscopy.
Nine patients with abdominal aortic aneurysms undergoing suprarenal fixation of stent grafts were included in the study. All patients received a Zenith endovascular graft with uncovered suprarenal components placed above the renal arteries. Renal ostial calcification and configuration of stent wires crossing the renal ostium were characterized in each patient and maximal transverse and longitudinal diameters of the renal ostia were measured on virtual endoscopy pre- and post-stent grafting.
There were altogether 17 renal ostia assessed with one patient having atrophic left kidney and no renal ostium being observed. Ostial calcification was found in five of the left renal ostia and five of the right renal ostia with one patient having bilateral ostial calcification. There was no significant difference between the renal ostial diameters measured pre- and post-stent grafting (p>0.05). Suprarenal stent struts were found to cross the renal ostia in various configurations observed on virtual endoscopy. All of the renal arteries were patent on follow-up CT scans after suprarenal fixation without stenosis or occlusion being observed. One patient with atrophic left renal artery developed renal failure following suprarenal stent grafting and received renal dialysis, while in the remaining cases median serum creatinine level did not change significantly.
Suprarenal stent struts did not significantly affect the renal ostia with ostial calcification in terms of the diameter measurements and renal function. Further studies deserve to investigate the long-term effect of stent struts on the renal artery in terms of cross-sectional area reduction caused by stent wires and ostial calcification.
目前对于穿过肾动脉开口处的支架支柱的行为及其对肾动脉开口形态的影响尚不清楚。本研究旨在探讨在CT虚拟血管内内窥镜检查中观察到的肾上段支架支柱是否会影响伴有开口钙化的肾动脉形态变化。
本研究纳入了9例接受肾上段支架移植物固定术的腹主动脉瘤患者。所有患者均接受了带裸肾上段组件的Zenith血管内移植物,该组件置于肾动脉上方。对每位患者的肾动脉开口钙化情况以及穿过肾动脉开口的支架金属丝形态进行了特征描述,并在植入支架移植物前后通过虚拟内窥镜测量了肾动脉开口的最大横径和纵径。
共评估了17个肾动脉开口,其中1例患者左肾萎缩,未观察到肾动脉开口。在左肾动脉开口中有5个发现开口钙化,右肾动脉开口中有5个发现开口钙化,1例患者双侧开口钙化。植入支架移植物前后测量的肾动脉开口直径无显著差异(p>0.05)。在虚拟内窥镜检查中观察到,肾上段支架支柱以各种形态穿过肾动脉开口。肾上段固定术后的随访CT扫描显示,所有肾动脉均通畅,未观察到狭窄或闭塞情况。1例左肾动脉萎缩的患者在肾上段植入支架移植物后出现肾衰竭并接受了肾透析,而其余病例中血清肌酐水平中位数无显著变化。
就直径测量和肾功能而言,肾上段支架支柱对伴有开口钙化的肾动脉开口没有显著影响。关于支架支柱因金属丝和开口钙化导致的横截面积减小对肾动脉的长期影响,值得进一步研究。