Shimura S, Inaba K, Ikeda S, Ishibashi A, Hirata Y, Osawa N
Department of Urology, Kitasato University Hospital.
Hinyokika Kiyo. 1992 Jan;38(1):37-41.
We studied the characteristics of Pseudomonas aeruginosa isolated from the urine specimens of the patients with urinary tract infections (UTI), in the urological unit at Kitasato University Hospital, between April, 1989 and March, 1990. Pseudomonas aeruginosa was detected in 8.0% of the total urine specimens (1.1% from outpatients, 6.9% from inpatients). Serotype of Pseudomonas aeruginosa was F (33%), G (17%), M (14%) and others (36%). In sensitivity tests, imipenem (IPM) had the lowest MIC among 8 antimicrobial agents tested, which were imipenem, piperacillin, cefsulodin, ceftazidime, aztreonam, gentamicin, amikacin, and ofloxacin with 5.0%, 82.0%, 74.0%, 69.0%, 92.0%, 67.0%, 79.0% and 82.0% resistant strains, respectively. Bladder cancer was the most common underlying disease in the urological patients with Pseudomonas infection. Pseudomonas aeruginosa infection is still an annoying problem in UTI among compromised patients suffering from advanced urinary tract malignancies.
我们研究了1989年4月至1990年3月期间,在北里大学医院泌尿外科,从尿路感染(UTI)患者尿液标本中分离出的铜绿假单胞菌的特征。在所有尿液标本中,8.0%检测出铜绿假单胞菌(门诊患者中为1.1%,住院患者中为6.9%)。铜绿假单胞菌的血清型为F(33%)、G(17%)、M(14%)及其他(36%)。在敏感性试验中,在测试的8种抗菌药物中,亚胺培南(IPM)的最低抑菌浓度最低,这8种抗菌药物分别是亚胺培南、哌拉西林、头孢磺啶、头孢他啶、氨曲南、庆大霉素、阿米卡星和氧氟沙星,耐药菌株比例分别为5.0%、82.0%、74.0%、69.0%、92.0%、67.0%、79.0%和82.0%。膀胱癌是铜绿假单胞菌感染的泌尿外科患者中最常见的基础疾病。在患有晚期尿路恶性肿瘤的免疫功能低下患者的尿路感染中,铜绿假单胞菌感染仍然是一个令人烦恼的问题。