Harms Craig A, Piccolo Rachel Lo, Rotstein David S, Hohn Aleta A
Department of Clinical Sciences and Environmental Medicine Consortium, College of Veterinary Medicine, Center for Marine Sciences and Technology, North Carolina State University, North Carolina 28557, USA.
J Wildl Dis. 2004 Jul;40(3):588-93. doi: 10.7589/0090-3558-40.3.588.
Massive urolithiasis of the penile urethra was observed in an adult pygmy sperm whale (Kogia breviceps) stranded on Topsail Island, North Carolina, USA. Calculi occupied the urethra from just distal to the sigmoid flexure to the tip of the penis for a length of 43 cm. A urethral diverticulum was present proximal to the calculi. The major portion of the multinodular urolith weighed 208 g and was 16 cm long x 3.7 cm diameter at the widest point. The urolith was composed of 100% struvite (magnesium ammonium phosphate) and on culture yielded Klebsiella oxytoca, a urease-positive bacterium occasionally associated with struvite urolith formation in domestic animals. Reaction to the calculi was characterized histologically by moderate multifocal to coalescing plasmacytic balanitis and penile urethritis. Role of the urethrolithiasis in the whale's stranding is speculative but could have involved pain or metabolic perturbations such as uremia or hyperammonemia.
在美国北卡罗来纳州托普赛尔岛搁浅的一头成年侏儒抹香鲸（小抹香鲸）中，观察到阴茎尿道存在大量尿石症。结石占据了尿道，从乙状弯曲的远端直至阴茎顶端，长度达43厘米。结石近端存在尿道憩室。多结节尿石的主要部分重208克，长16厘米，最宽处直径为3.7厘米。该尿石由100%的鸟粪石（磷酸镁铵）组成，培养后发现产酸克雷伯菌，这是一种脲酶阳性细菌，在家畜中偶尔与鸟粪石尿石形成有关。组织学上，对结石的反应表现为中度多灶性至融合性浆细胞性龟头炎和阴茎尿道炎。尿石症在鲸鱼搁浅中所起的作用具有推测性，但可能涉及疼痛或代谢紊乱，如尿毒症或高氨血症。
