Willoughby Darryn S
Exercise and Biochemical Nutrition Laboratory, Dept of Health, Human Performance, and Recreation, Baylor University, Waco, TX 76798-7313, USA.
Int J Sport Nutr Exerc Metab. 2004 Aug;14(4):461-72. doi: 10.1123/ijsnem.14.4.461.
This study examined 12 wk of resistance training and cystoseira canariensis supplementation on serum levels of myostatin and follistatin-like related gene (FLRG) and muscle strength and body composition. Twenty-two untrained males were randomly assigned to a placebo (PLC) or myostatin binder (MYO) group in a double-blind fashion. Blood was obtained before and after 6 and 12 wk of training. PLC and MYO trained thrice weekly using 3 sets of 6 to 8 repetitions at 85 % to 90 % 1 repetition maximum. MYO ingested 1200 mg/d of cystoseira canariensis. Data were analyzed with 2-way ANOVA. After training, total body mass, fat-free mass, muscle strength, thigh volume/mass, and serum myostatin and FLRG increased for both groups (P < 0.05); however, there were no differences between groups (P > 0.05). Twelve wk of heavy resistance training and 1200 mg/d of cystoseira canariensis supplementation appears ineffective at inhibiting serum myostatin and increasing muscle strength and mass or decreasing fat mass.
本研究考察了为期12周的抗阻训练以及补充加那利囊链藻对肌肉生长抑制素和类卵泡抑素相关基因（FLRG）血清水平、肌肉力量和身体成分的影响。22名未经训练的男性被双盲随机分配到安慰剂（PLC）组或肌肉生长抑制素结合剂（MYO）组。在训练6周和12周前后采集血液样本。PLC组和MYO组每周进行三次训练，每组85%至90%的1次最大重复量，进行3组，每组6至8次重复。MYO组每天摄入1200毫克加那利囊链藻。数据采用双向方差分析。训练后，两组的总体重、去脂体重、肌肉力量、大腿体积/质量以及血清肌肉生长抑制素和FLRG均增加（P<0.05）；然而，两组之间无差异（P>0.05）。为期12周的高强度抗阻训练以及每天补充1200毫克加那利囊链藻似乎在抑制血清肌肉生长抑制素、增加肌肉力量和质量或减少脂肪量方面无效。
