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经内镜超声引导下细针穿刺对非原发性胰腺肿瘤的诊断

Diagnosis of nonprimary pancreatic neoplasms by endoscopic ultrasound-guided fine-needle aspiration.

作者信息

Mesa Hector, Stelow Edward B, Stanley Michael W, Mallery Shawn, Lai Rebecca, Bardales Ricardo H

机构信息

Department of Pathology, University of Minnesota, Minneapolis, Minnesota 55455, USA.

出版信息

Diagn Cytopathol. 2004 Nov;31(5):313-8. doi: 10.1002/dc.20142.

DOI:10.1002/dc.20142
PMID:15468134
Abstract

Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a proven modality for the diagnosis of primary pancreatic neoplasms. We describe our experience in diagnosing nonprimary pancreatic tumors by EUS-FNA. Cytology files were searched for all EUS-FNA of the pancreas for the period 2000-2002. All cases diagnosed as neoplasms were selected and those diagnosed as nonprimary pancreatic tumors were reviewed and analyzed. One hundred ninety-one of 468 cases were diagnosed as neoplasms. Eleven of these cases were diagnosed as nonprimary pancreatic tumors (2.4% of all diagnoses and 5.7% of all neoplasms). The diagnoses were supported by clinical history (n = 7), cytological findings (n = 11), cell block histology (n = 11), cell block immunohistochemistry (n = 6), and flow cytometry (n = 1). EUS-FNA is a safe and minimally invasive method for the diagnosis of nonprimary pancreatic neoplasms. Evaluation of clinical history, cytomorphology, and ancillary techniques, especially those applied to cell block material, are essential for accurate diagnoses.

摘要

内镜超声引导下细针穿刺抽吸术(EUS-FNA)是诊断原发性胰腺肿瘤的一种已被证实的方法。我们描述了我们通过EUS-FNA诊断非原发性胰腺肿瘤的经验。检索了2000年至2002年期间所有胰腺EUS-FNA的细胞学档案。选择所有诊断为肿瘤的病例,并对那些诊断为非原发性胰腺肿瘤的病例进行回顾和分析。468例病例中有191例被诊断为肿瘤。其中11例被诊断为非原发性胰腺肿瘤(占所有诊断的2.4%,占所有肿瘤的5.7%)。诊断得到临床病史(n = 7)、细胞学检查结果(n = 11)、细胞块组织学(n = 11)、细胞块免疫组织化学(n = 6)和流式细胞术(n = 1)的支持。EUS-FNA是诊断非原发性胰腺肿瘤的一种安全且微创的方法。评估临床病史、细胞形态学和辅助技术,尤其是应用于细胞块材料的技术,对于准确诊断至关重要。

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