George Tracy I, Jeng Michael, Berquist William, Cherry Athena M, Link Michael P, Arber Daniel A
Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
Pediatr Blood Cancer. 2005 Mar;44(3):270-6. doi: 10.1002/pbc.20231.
Post-transplantation lymphoproliferative disorders (PTLD) are a well-recognized complication of solid organ transplantation. The vast majority of PTLD are Epstein-Barr virus (EBV)-related infections that manifest as B-cell malignancies. We report an unusual case of an EBV-associated T-cell lymphoma in a 10-year-old boy who had previously undergone liver transplantation at age 4 years. He presented with hemophagocytic syndrome (HPS) and active EBV infection, with positive serum titers and polymerase chain reaction (PCR) for EBV in blood, colon, and antral samples.
移植后淋巴组织增生性疾病（PTLD）是实体器官移植中一种公认的并发症。绝大多数PTLD是与EB病毒（EBV）相关的感染，表现为B细胞恶性肿瘤。我们报告了一例罕见的EBV相关T细胞淋巴瘤病例，患者为一名10岁男孩，曾在4岁时接受过肝移植。他表现为噬血细胞综合征（HPS）和活动性EBV感染，血液、结肠和胃窦样本中的EBV血清滴度和聚合酶链反应（PCR）均为阳性。
