Kagialis-Girard Sandrine, Mialou Valerie, Ffrench Martine, Dupuis-Girod Sophie, Pages Marie-Pierre, Bertrand Yves
Hematology Laboratory, Hôpital Debrousse, Lyon, France.
Pediatr Blood Cancer. 2005 Feb;44(2):190-2. doi: 10.1002/pbc.20222.
We report two cases of visceral larva migrans (VLM) syndrome by Toxocara in children. The biological presentation was unusual and characterized by persistent secondary thrombocytosis (>1,000 x 10(9)/L) mimicking an essential thrombocythemia and variable hypereosinophilia syndrome. Both children had non-specific symptoms including abdominal pain, skin rash, and fever. The diagnosis was confirmed by serology. The children were treated with either thiabendazole or albendazole, resulting in normalization of eosinophil and platelet counts.
我们报告了两例儿童因弓蛔虫引起的内脏幼虫移行症(VLM)综合征。生物学表现不寻常,其特征为持续性继发性血小板增多症(>1,000×10⁹/L),类似原发性血小板增多症以及可变的高嗜酸性粒细胞综合征。两名儿童均有腹痛、皮疹和发热等非特异性症状。通过血清学确诊。两名儿童接受了噻苯达唑或阿苯达唑治疗,嗜酸性粒细胞和血小板计数恢复正常。