Kolesnichenko A P, Gritsan G V, Gritsan A I, Skorobogatov A Iu
Anesteziol Reanimatol. 2004 Jul-Aug(4):41-4.
The clinical course of thrombohemorrhagic complications was studied in 56 patients, aged 18 to 38, with sepsis, which developed due to obstetric and gynecologic processes on days 1, 3, 5, 7 and 10 after surgery. The patients were treated, 1999-2003, at the obstetric intensive-care and consultation center, MUZA Maternity Hospital No. 1, Krasnoyarsk. The coagulation, anti-coagulation and fibrinolytic chains of the coagulation cascade and vascular-thrombotic hemostasis were dynamically evaluated. Thrombohemorrhagic complications in severe sepsis and septic shock manifested themselves as hypercoagulation stage in 52% of observations. The hemostasis correction does not only require the elimination of changes in the hemocoagulation system but also the intensive care of the present systemic dysfunctions.
对56例年龄在18至38岁、患有败血症的患者的血栓出血并发症临床病程进行了研究，这些败血症是由1999 - 2003年在克拉斯诺亚尔斯克市第一穆扎妇产医院产科重症监护和咨询中心进行的手术（产科和妇科手术）后第1、3、5、7和10天发生的产科和妇科疾病引起的。对凝血级联反应的凝血、抗凝和纤维蛋白溶解链以及血管血栓止血进行了动态评估。严重败血症和感染性休克中的血栓出血并发症在52%的观察病例中表现为高凝阶段。止血纠正不仅需要消除血液凝固系统的变化，还需要对当前的全身功能障碍进行重症监护。
