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[危急状态下颅脑创伤患者血脑屏障功能的评估]

[Evaluation of the function of the hematoencephalic barrier in victims with craniocerebral trauma in critical state].

作者信息

Nikiforova N V, Churliaev Iu A, Kan S L, Arkhipova S V, Romanova T V

出版信息

Anesteziol Reanimatol. 2004 Jul-Aug(4):52-4.

Abstract

Estimates of the relative-entry coefficient, molecular profile of the cerebrospinal fluid and of the molecular blood profile based on the comparison of concentrations of proteins with different physical-and-chemical properties enable an evaluation of the function of the hematoencephalic barrier in victims with craniocerebral trauma in critical state. It was possible to state, with such approach in use, that the regulatory and protective functions of the hematoencephalic barrier were changing differently in favorable and unfavorable trauma outcomes, which must be duly considered in choosing a treatment tactics for the above category of victims.

摘要

通过比较具有不同理化性质的蛋白质浓度来估计相对进入系数、脑脊液的分子特征和血液的分子特征,能够评估处于危急状态的颅脑创伤患者血脑屏障的功能。采用这种方法可以指出,血脑屏障的调节和保护功能在创伤预后良好和不良的情况下变化不同,在为上述这类患者选择治疗策略时必须充分考虑这一点。

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