Gianotti-Crosti syndrome caused by acute hepatitis B virus genotype D infection.

作者信息

Michitaka Kojiro, Horiike Norio, Chen Yan, Duong Tran Nhu, Konishi Ichiro, Mashiba Toshie, Tokumoto Yoshio, Hiasa Yoichi, Tanaka Yasuhito, Mizokami Masashi, Onji Morikazu

机构信息

Endoscopy Center, Ehime University School of Medicine, Shigenobucho, Onsen-gun, Ehime 791-0295.

出版信息

Intern Med. 2004 Aug;43(8):696-9. doi: 10.2169/internalmedicine.43.696.

DOI:10.2169/internalmedicine.43.696

PMID:15468968

Abstract

A 12-year-old girl with Gianotti-Crosti syndrome caused by hepatitis B virus (HBV) infection was admitted due to eruption on her extremities. Laboratory findings revealed elevation of transaminase, positivity for HB surface antigen (HBsAg), and an IgM type anti-HB core. The eruption and level of transaminase improved, and HBsAg became negative within 2 months of onset. Analysis of the virus revealed it to be genotype D with a genomic length of 3,182 bases and the HBsAg serotype was ayw3, which is very rare in Japan. The possible relationship between Gianotti-Crosti syndrome and HBV genotype D infection is discussed.

摘要