位于十二指肠第三部的巨大生长抑素瘤伴严重葡萄糖不耐受。

Large duodenal somatostatinoma in the third portion associated with severe glucose intolerance.

作者信息

Kimura Ryosuke, Hayashi Yoshinari, Takeuchi Toyo, Shimizu Manabu, Hiratsuka Maki, Yoshida Michihiro, Hamajima Eiji, Iwata Masaru, Imoto Masami, Hattori Hideo

机构信息

Department of Internal Medicine, Kariya General Hospital, 5-15 Sumiyoshi-cho Kariya, Aichi 448-8505.

出版信息

Intern Med. 2004 Aug;43(8):704-7. doi: 10.2169/internalmedicine.43.704.

DOI:10.2169/internalmedicine.43.704

PMID:15468970

Abstract

A 51-year-old man was admitted with hyperglycemia and a duodenal tumor. Although his glycemic control was poor, basal C-peptide levels were not suppressed. Further examination revealed a mass measuring 7.8 cm in diameter in the third portion of the duodenum. Duodenectomy revealed a slow-growing sessile tumor located near Treitz's ligament. The immunohistochemical profile of sections of the specimen revealed the presence of somatostatin. The patient's serum somatostatin was elevated to 300 pg/ml preoperatively, but was reduced to 10 pg/ml postoperatively. Glycemic control also normalized after the operation.

摘要

一名51岁男性因高血糖和十二指肠肿瘤入院。尽管他的血糖控制不佳，但基础C肽水平未受抑制。进一步检查发现十二指肠第三段有一个直径7.8厘米的肿块。十二指肠切除术显示在Treitz韧带附近有一个生长缓慢的无蒂肿瘤。标本切片的免疫组化分析显示存在生长抑素。患者术前血清生长抑素升高至300 pg/ml，但术后降至10 pg/ml。术后血糖控制也恢复正常。