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壶腹生长抑素瘤:结直肠癌切除术后的意外术后发现。

Somatostatinoma of the Ampulla: An Incidental Postoperative Finding Following Colorectal Cancer Resection.

作者信息

French Joshua B, Pawa Rishi

机构信息

Department of Medicine, Division of Gastroenterology, Wake Forest Baptist Hospital, Winston-Salem, NC.

出版信息

ACG Case Rep J. 2016 Jan 20;3(2):109-11. doi: 10.14309/crj.2016.16. eCollection 2016 Jan.

DOI:10.14309/crj.2016.16
PMID:26958562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4748198/
Abstract

Somatostatinoma of the gastrointestinal tract is a rare finding, especially arising from the ampulla of Vater. We present a man recently diagnosed with rectal adenocarcinoma who was found on imaging to have an ampullary mass. Histology and immunohistochemical staining of the biopsied tissue were consistent with a nonfunctioning somatostatinoma. The patient had neurofibromatosis, which have been reported in patients with ampullary somatostatinomas. Our case highlights the importance of gastrointestinal findings in those with underlying genetic conditions.

摘要

胃肠道生长抑素瘤是一种罕见的疾病,尤其是起源于 Vater 壶腹的情况。我们报告了一名近期被诊断为直肠腺癌的男性患者,影像学检查发现其有壶腹肿物。活检组织的组织学和免疫组化染色结果与无功能生长抑素瘤相符。该患者患有神经纤维瘤病,此前曾有壶腹生长抑素瘤患者被报道患有此病。我们的病例强调了在有潜在遗传疾病的患者中进行胃肠道检查的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/64cb50cf9e2a/crj-03-109-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/b267ae15b61b/crj-03-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/5c13ad9f104a/crj-03-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/93ed4ba61b5c/crj-03-109-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/64cb50cf9e2a/crj-03-109-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/b267ae15b61b/crj-03-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/5c13ad9f104a/crj-03-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/93ed4ba61b5c/crj-03-109-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d47/4748198/64cb50cf9e2a/crj-03-109-g004.jpg

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引用本文的文献

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Somatostatinoma: Beyond neurofibromatosis type 1 (Review).生长抑素瘤:超越1型神经纤维瘤病(综述)
Exp Ther Med. 2020 Oct;20(4):3383-3388. doi: 10.3892/etm.2020.8965. Epub 2020 Jul 3.

本文引用的文献

1
Duodenal somatostatinoma: a case report and review of the literature.十二指肠生长抑素瘤:一例病例报告及文献综述
J Med Case Rep. 2013 Apr 25;7:115. doi: 10.1186/1752-1947-7-115.
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Duodenal somatostatinoma: a case report and review.十二指肠生长抑素瘤:一例报告并文献复习。
Korean J Intern Med. 2011 Mar;26(1):103-7. doi: 10.3904/kjim.2011.26.1.103. Epub 2011 Mar 2.
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Periampullary and duodenal neoplasms in neurofibromatosis type 1: two cases and an updated 20-year review of the literature yielding 76 cases.1 型神经纤维瘤病中的壶腹周围和十二指肠肿瘤:两例病例及对文献的 20 年回顾,共 76 例。
J Gastrointest Surg. 2010 Jun;14(6):1052-61. doi: 10.1007/s11605-009-1123-0. Epub 2010 Mar 19.
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Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient.同一患者十二指肠和胰头部的两个同步生长的生长抑素瘤。
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Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity.十二指肠和胰腺产生生长抑素的神经内分泌肿瘤:发病率、类型、生物学行为、与遗传性综合征的关联及功能活性。
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Large duodenal somatostatinoma in the third portion associated with severe glucose intolerance.位于十二指肠第三部的巨大生长抑素瘤伴严重葡萄糖不耐受。
Intern Med. 2004 Aug;43(8):704-7. doi: 10.2169/internalmedicine.43.704.
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Periampullary pancreatic somatostatinoma.壶腹周围胰腺生长抑素瘤
Ann Surg Oncol. 2002 Nov;9(9):869-74. doi: 10.1007/BF02557523.
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Somatostatinoma of the ampulla of Vater.壶腹生长抑素瘤
Gastrointest Endosc. 1996 Nov;44(5):612-4. doi: 10.1016/s0016-5107(96)70021-4.
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Von Recklinghausen's disease associated with duodenal somatostatinoma: contrast of duodenal versus pancreatic somatostatinomas.与十二指肠生长抑素瘤相关的冯雷克林霍增氏病:十二指肠生长抑素瘤与胰腺生长抑素瘤的对比
J Surg Oncol. 1995 May;59(1):67-73. doi: 10.1002/jso.2930590116.
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Somatostatinoma: a case report and review of the literature.生长抑素瘤:一例病例报告及文献综述
J Surg Oncol. 1987 Sep;36(1):8-16. doi: 10.1002/jso.2930360104.