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穿透性腹部创伤患者死亡率的预测因素

Predicting factors for mortality in the penetrating abdominal trauma.

作者信息

Aldemir M, Taçyildiz I, Girgin S

机构信息

Department of General Surgery, Dicle University, Faculty of Medicine, Turkey.

出版信息

Acta Chir Belg. 2004 Aug;104(4):429-34.

Abstract

PURPOSE

penetrating abdominal trauma (PAT) is still a serious problem all over the world. This study was made to define and discuss the factors that could affect mortality in the PAT.

METHODS

the records of 1048 patients hospitalized and operated for PAT at Dicle University Hospital (DUH) between January 1990 and December 2001 were retrospectively reviewed. Patients (n = 1048) were divided into two groups: "Healthy Group" (HG) (n = 942) and "Deathly Group" (DG) (n = 106). The epidemiological and clinical features were evaluated as probable risk factors for mortality. The risk factors for mortality were revealed using univariate and multivariate analyses.

RESULTS

a total of 1048 patients [937 (89.4%) male, 111(10.6%) female] with PAT were included in this study. The mortality rate (22.5%) of female patients was significantly higher than (8.6%) that of male patients (p = 0.000). The mean age was 30.01+/-63.9 (14-74) years and 30+/-12.5(15-71) years in the HG and DG consecutively (p = 0.85). The average interval between injury and operation (IBIO) was 2.09+/-1.3 (0.5-3) and 6.9+/-11.4 (1-6.1) hours in the HG and DG respectively (p = 0.000). Presence of shock on admission (PSDA) was determined in 87 patients and in 96 patients in the HG and DG respectively (p = 0.000). The mortality rate (14.9%) in patients presenting gunshot wounds (GSW) was significantly higher than (2.7%) that of patients with stab wounds (SW) (p = 0.000). The average number of injured intraabdominal organs (NIAOI) was 1.98+/-1.08 (1-7) and 4.67+/-1.99 (1-13) in the HG and DG respectively (p = 0.000). Mortality rates were 72.7% in cardiac injury, 30% in great vessels injuries, 32.6% in cranial injury, and 21.5% in major extremity and pelvic injury (p = 0.000). The average penetrating abdominal trauma index (PATI) was 11.78+/-9.44 (1-58) and 46.24+/-22.18 (15-119) in the HG and DG respectively (p = 0.000). In multivariate analyses, female gender [Odds Ratio (OR) = 10.74, 95% Confidence Interval (CI) = 3.03-38.12, P = 0.000], the long IBIO (OR = 1.82, CI = 1.39-2.40, P = 0.000), PSDA (OR = 94.45, CI = 28.32-314.95, P = 0.000), presence of cranial injury (OR = 0.03, CI = 0.002-0.363, P = 0.006) and high PATI (OR = 1.14, CI = 1.09-1.19, P = 0.000), were found significantly important for mortality.

CONCLUSION

we determined that conditions such as, female gender, long interval between injury and operation, presence of shock on admission, presence of cranial injury and high PATI were predicting factors for mortality in PAT.

摘要

目的

穿透性腹部创伤(PAT)在全球范围内仍是一个严重问题。本研究旨在确定并探讨可能影响PAT患者死亡率的因素。

方法

回顾性分析1990年1月至2001年12月在迪克莱大学医院(DUH)因PAT住院并接受手术治疗的1048例患者的病历。将患者(n = 1048)分为两组:“健康组”(HG)(n = 942)和“死亡组”(DG)(n = 106)。评估流行病学和临床特征作为可能的死亡危险因素。采用单因素和多因素分析揭示死亡危险因素。

结果

本研究共纳入1048例PAT患者[937例(89.4%)男性,111例(10.6%)女性]。女性患者的死亡率(22.5%)显著高于男性患者的死亡率(8.6%)(p = 0.000)。HG组和DG组的平均年龄分别为30.01±63.9(14 - 74)岁和30±12.5(15 - 71)岁(p = 0.85)。HG组和DG组受伤至手术的平均间隔时间(IBIO)分别为2.09±1.3(0.5 - 3)小时和6.9±11.4(1 - 6.1)小时(p = 0.000)。HG组和DG组分别有87例和96例患者入院时存在休克(PSDA)(p = 0.000)。枪伤(GSW)患者的死亡率(14.9%)显著高于刺伤(SW)患者的死亡率(2.7%)(p = 0.000)。HG组和DG组腹腔内受伤器官的平均数量(NIAOI)分别为1.98±1.08(1 - 7)个和4.67±1.99(1 - 13)个(p = 0.000)。心脏损伤的死亡率为72.7%,大血管损伤为30%,颅脑损伤为32.6%,主要肢体和骨盆损伤为21.5%(p = 0.000)。HG组和DG组的平均穿透性腹部创伤指数(PATI)分别为11.78±9.44(1 - 58)和46.24±22.18(15 - 119)(p = 0.000)。多因素分析显示,女性性别[比值比(OR) = 10.74,95%置信区间(CI) = 3.03 - 38.12,P = 0.000]、较长的IBIO(OR = 1.82,CI = 1.39 - 2.40,P = 0.000)、PSDA(OR = 94.45,CI = 28.32 - 314.95,P = 0.000)、存在颅脑损伤(OR = 0.03,CI = 0.002 - 0.363,P = 0.006)和较高的PATI(OR = 1.14,CI = 1.09 - 1.19,P = 0.000)对死亡率有显著影响。

结论

我们确定女性性别、受伤至手术间隔时间长、入院时存在休克、存在颅脑损伤和较高的PATI等情况是PAT患者死亡的预测因素。

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