Girgin Sadullah, Gedik Ercan, Uysal Ersin, Taçyildiz Ibrahim Halil
Department of General Surgery, Dicle University, Diyarbakir, Turkey.
Ulus Travma Acil Cerrahi Derg. 2009 May;15(3):232-8.
The present study explored the factors effective on colon-related morbidity in patients with penetrating injury of the colon.
The medical records of 196 patients were reviewed for variables including age, gender, factor of trauma, time between injury and operation, shock, duration of operation, Penetrating Abdominal Trauma Index (PATI), Injury Severity Score (ISS), site of colon injury, Colon Injury Score, fecal contamination, number of associated intra- and extraabdominal organ injuries, units of transfused blood within the first 24 hours, and type of surgery. In order to determine the independent risk factors, multivariate logistic regression analysis was performed.
Gunshot wounds, interval between injury and operation > or =6 hours, shock, duration of the operation > or =6 hours, PATI > or =25, ISS > or =20, Colon Injury Score > or = grade 3, major fecal contamination, number of associated intraabdominal organ injuries >2, number of associated extraabdominal organ injuries >2, multiple blood transfusions, and diversion were significantly associated with morbidity. Multivariate logistic regression analysis showed diversion and transfusion of > or =4 units in the first 24 hours as independent risk factors affecting colon-related morbidity.
Diversion and transfusion of > or =4 units in the first 24 hours were determined to be independent risk factors for colon-related morbidity.
本研究探讨了影响结肠穿透伤患者结肠相关发病率的因素。
回顾了196例患者的病历,记录了年龄、性别、创伤因素、受伤至手术的时间、休克情况、手术时长、穿透性腹部创伤指数(PATI)、损伤严重程度评分(ISS)、结肠损伤部位、结肠损伤评分、粪便污染情况、腹内和腹外相关器官损伤数量、伤后24小时内输血单位数以及手术类型等变量。为确定独立危险因素,进行了多因素逻辑回归分析。
枪伤、受伤至手术间隔≥6小时、休克、手术时长≥6小时、PATI≥25、ISS≥20、结肠损伤评分≥3级、严重粪便污染、腹内相关器官损伤数量>2、腹外相关器官损伤数量>2、多次输血以及造瘘与发病率显著相关。多因素逻辑回归分析显示,造瘘以及伤后24小时内输血≥4单位是影响结肠相关发病率的独立危险因素。
伤后24小时内造瘘以及输血≥4单位被确定为结肠相关发病率的独立危险因素。