An investigation into causes and effects of high cyanide levels in the palladium-catalyzed cyanation reaction.
作者信息
Marcantonio Karen M, Frey Lisa F, Liu Yong, Chen Yadan, Strine Jeff, Phenix Brian, Wallace Debra J, Chen Cheng-yi
机构信息
Department of Process Research, Merck Research Laboratories, P.O. Box 2000 Rahway, New Jersey 07065, USA.
出版信息
Org Lett. 2004 Oct 14;6(21):3723-5. doi: 10.1021/ol048643x.
PMID:15469333
Abstract
[reaction: see text] The palladium-catalyzed cyanation reaction is known to be sensitive to dissolved cyanide. Investigation into some causes of high levels of dissolved cyanide is presented here, along with a robust solution to this problem.
摘要
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