钯催化吲哚 C-H 键与碳酸氢铵和二甲基亚砜结合的氰化反应，作为一种安全的氰源。
The palladium-catalyzed cyanation of indole C-H bonds with the combination of NH4HCO3 and DMSO as a safe cyanide source.
机构信息
College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325000, People's Republic of China.
出版信息
Chem Commun (Camb). 2011 Jun 21;47(23):6725-7. doi: 10.1039/c1cc11603g. Epub 2011 May 10.
PMID:21556432
Abstract
A palladium-catalyzed cyanation of the 3-position of indole sp(2) C-H bonds by the combination of NH(4)HCO(3) and DMSO as the "CN" source was achieved to provide aromatic nitriles in moderate to good yields with excellent regioselectivity. It represents a practical and safe cyanation method.
摘要
钯催化吲哚 sp(2) C-H 键 3 位氰化反应，通过 NH(4)HCO(3) 和 DMSO 组合作为 "CN" 源，以中等至良好的收率和优异的区域选择性得到芳族腈。它代表了一种实用且安全的氰化方法。
Zotero 插件