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[慢性细菌性前列腺炎患者抗生素治疗的临床反应研究]

[A study of clinical response to antibiotic treatment in subjects with chronic bacterial prostatitis].

作者信息

Gutiérrez J, Carlos S, Martínez J L, Liébana J L, Soto M J, Luna J de Dios, Piédrola G

机构信息

Departamento de Microbiología, Hospital Universitario San Cecilio, Universidad de Granada, Granada.

出版信息

Rev Esp Quimioter. 2004 Jun;17(2):189-92.

PMID:15470514
Abstract

A study was carried out on the clinical response to antibiotics in 105 patients with chronic bacterial prostatitis. Two groups of patients were compared in a retrospective study. The results of rectal examination, ultrasound scan, microbiological analysis, and response to different antibiotic therapy regimens were compared. There was a high incidence of perineal-testicular pain and sexual potency reduction; prostate congestion and pain on rectal examination were frequently reported. All the patients had positive microbial cultures, with Gram-negative microorganisms being predominantly isolated. Following the administration of different antibiotic therapy regimens, symptoms either disappeared or diminished, irrespective of whether positive cultures remained. A poorer clinical response was observed in patients with positive prostate ultrasound and rectal examination, and with isolated Gram-negative bacilli. No differences were observed between either group in clinical response to different antimicrobial regimens.

摘要

对105例慢性细菌性前列腺炎患者使用抗生素的临床反应进行了一项研究。在一项回顾性研究中对两组患者进行了比较。比较了直肠指检、超声扫描、微生物分析结果以及对不同抗生素治疗方案的反应。会阴部-睾丸疼痛和性功能减退的发生率很高;经常报告直肠指检时前列腺充血和疼痛。所有患者的微生物培养均为阳性,主要分离出革兰氏阴性微生物。给予不同的抗生素治疗方案后,症状要么消失要么减轻,无论培养结果是否仍为阳性。前列腺超声和直肠指检阳性且分离出革兰氏阴性杆菌的患者临床反应较差。两组在对不同抗菌方案的临床反应方面未观察到差异。

相似文献

1
[A study of clinical response to antibiotic treatment in subjects with chronic bacterial prostatitis].[慢性细菌性前列腺炎患者抗生素治疗的临床反应研究]
Rev Esp Quimioter. 2004 Jun;17(2):189-92.
2
[Approaches to the study of chronic bacterial prostatitis].
Arch Esp Urol. 1989 Jul-Aug;42(6):515-8.
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Detection of bacterial signal by 16S rRNA polymerase chain reaction in expressed prostatic secretions predicts response to antibiotic therapy in men with chronic pelvic pain syndrome.通过16S rRNA聚合酶链反应检测前列腺分泌物中的细菌信号可预测慢性盆腔疼痛综合征男性对抗生素治疗的反应。
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Treatment of chronic bacterial prostatitis with amikacin through anal submucosal injection.阿米卡星经肛门黏膜下注射治疗慢性细菌性前列腺炎
Asian J Androl. 2002 Sep;4(3):163-7.
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Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis.非传统细菌性尿路病原体在慢性前列腺炎管理中的临床意义
J Urol. 2008 Apr;179(4):1391-5. doi: 10.1016/j.juro.2007.11.081. Epub 2008 Mar 4.
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On chronic prostatitis with special studies of Staphylococcus epidermidis.关于慢性前列腺炎及表皮葡萄球菌的专项研究
Scand J Urol Nephrol Suppl. 1989;123:1-36.
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[Local antibiotic therapy in the treatment of chronic bacterial prostatitis].[局部抗生素疗法治疗慢性细菌性前列腺炎]
Arch Esp Urol. 1980 May-Jun;33(3):261-6.
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[Detection of bacterial signal of 16S rRNA gene in prostate tissues obtained by perineal approach from patient with chronic pelvic pain syndrome].[经会阴途径获取的慢性盆腔疼痛综合征患者前列腺组织中16S rRNA基因细菌信号的检测]
Zhonghua Yi Xue Za Zhi. 2009 Mar 31;89(12):823-5.
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[Laboratory and clinical study of ofloxacin in the treatment of bacterial prostatitis].
Hinyokika Kiyo. 1984 Oct;30(10):1505-18.
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Management of bacterial prostatitis: what's new?细菌性前列腺炎的管理:有哪些新进展?
BJU Int. 2008 Mar;101 Suppl 3:7-10. doi: 10.1111/j.1464-410X.2008.07495.x.

引用本文的文献

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[Microbial etiology of bacterial chronic prostatitis: systematic review].[细菌性慢性前列腺炎的微生物病因学:系统评价]
Rev Esp Quimioter. 2023 Apr;36(2):144-151. doi: 10.37201/req/099.2022. Epub 2023 Jan 9.