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动静脉内瘘的临床及器械监测

[Clinical and instrumental surveillance of the arteriovenous fistula].

作者信息

Quarello F, Forneris G, Pozzato M

机构信息

Divisione di Nefrologia e Dialisi, Ospedale San Giovanni Bosco, Torino.

出版信息

G Ital Nefrol. 2004 Jul-Aug;21(4):317-30.

Abstract

Stenosis and thrombosis are the most important complications leading to vascular access failure in hemodialysis (HD). Aiming for an early access dysfunction diagnosis and elective repair of the failing access, the DOQI guidelines recommend that all HD patients undergo a program of regular monitoring and surveillance. The K/DOQI 2000 update identifies specific types of evaluation for dialysis accesses. First nephrologists should examine patients by inspecting, ausculting and palpating the access at least every 4-6 weeks when patients are not being dialyzed. In addition, access surveillance should be regularly performed by various techniques, i.e. urea recirculation test, dialysis venous pressure measurement and access blood flow assessment. Recently many methods have been proposed and implemented. Ultrasound dilution is the most commonly used. This technique relies on the change in ultrasound velocity when blood is diluted with a normal saline bolus at a known dialyzer blood flow rate, after the lines have been reversed. Following the use of blood ultrasound dilution, multiple technologies have been implemented for access flow measurement with line reversal, i.e. hematocrit (Hct) dilution, thermodilution, conductivity variation assessment. There are three other methods that do not require line reversal: i.e. transcutaneous access flow (TQA) assessment, glucose pump test (GPT) and the variable flow Doppler. Finally, duplex scanning can provide both the anatomy and blood flow of the access. With a Qa <600 mL/min or <1000 mL/min, but reduced by 25% in 4 months, K/DOQI suggest performing angiography and eventual elective repair.

摘要

狭窄和血栓形成是导致血液透析(HD)血管通路失败的最重要并发症。为了早期诊断通路功能障碍并对失功通路进行择期修复,《肾脏病预后质量倡议(DOQI)指南》建议所有HD患者接受定期监测和检查。《2000年K/DOQI更新版》确定了透析血管通路的特定评估类型。首先,肾病科医生应在患者未进行透析时,至少每4至6周通过检查、听诊和触诊来检查患者的血管通路。此外,应通过多种技术定期进行通路监测,即尿素再循环试验、透析静脉压力测量和通路血流量评估。最近提出并实施了许多方法。超声稀释是最常用的方法。该技术依赖于在管路反转后,以已知的透析器血流量用生理盐水团注稀释血液时超声速度的变化。在使用血液超声稀释之后,已经实施了多种在管路反转情况下进行通路血流量测量的技术,即血细胞比容(Hct)稀释、热稀释、电导率变化评估。还有另外三种不需要管路反转的方法:即经皮通路血流量(TQA)评估、葡萄糖泵试验(GPT)和可变流量多普勒。最后,双功扫描可以提供通路的解剖结构和血流量。当血流量(Qa)<600 mL/分钟或<1000 mL/分钟,但在4个月内降低了25%时,K/DOQI建议进行血管造影并最终进行择期修复。

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