Daniels John Spencer M
Department of Oral & Maxillofacial Surgery, Saudi Arabia.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Oct;98(4):409-13. doi: 10.1016/j.tripleo.2004.01.015.
Only 2% of all primary hyperparathyroidism cases occur in patients below the age of 30 years. Owing to the improved methods of blood analysis in the last 2 decades, most of the recent cases of primary hyperparathyroidism are diagnosed early and asymptomatically. This makes advanced disease with bone lesions extremely rare these days. A case of a 25-year old female patient with previously undiagnosed primary hyperparathyroidism who presented first with palatal swelling is reported. Further investigations revealed parathyroid adenoma, nephrocalcinosis, and extensive bone lesions involving the maxillary sinus and palate as well as the pelvic bone. The evaluation of the hyperparathyroid patient is reviewed in this report. The methods of treatment of the bony lesions of primary hyperparathyroidism are also discussed.
所有原发性甲状旁腺功能亢进病例中,仅2%发生在30岁以下的患者。由于过去20年血液分析方法的改进,近期大多数原发性甲状旁腺功能亢进病例得以早期且无症状地被诊断出来。如今,伴有骨病变的晚期疾病极为罕见。本文报告了一例25岁女性患者,此前未被诊断出患有原发性甲状旁腺功能亢进,最初表现为腭部肿胀。进一步检查发现甲状旁腺腺瘤、肾钙质沉着症,以及累及上颌窦、腭部和骨盆骨的广泛骨病变。本报告对甲状旁腺功能亢进患者的评估进行了综述。还讨论了原发性甲状旁腺功能亢进骨病变的治疗方法。