Dhiwakar M, Damodharan S, Rajeshwari K M, Mehta S
B-ENT. 2016;12(1):73-6.
Giant cell reparative granuloma of the facial skeleton is a rare presentation of hyperparathyroidism.
A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery.
Biopsies confirmed giant cell reparative granuloma. Blood testing revealed very high parathyroid hormone levels, and brown tumours due to primary hyperparathyroidism weresuspected. Surgical removal of an ectopic adenoma led to correction of the endocrine condition.
To our knowledge, this is the first reported case of multiple brown tumours of the facial skeleton due to an ectopic parathyroid adenoma. Diagnostic pitfalls and therapeutic challenges are described.
面部骨骼巨细胞修复性肉芽肿是甲状旁腺功能亢进的一种罕见表现。
一名17岁女孩出现下颌骨和上颌骨进行性膨胀性骨质生长。通过活检、血液检查、影像学检查和手术对该病例进行了研究。
活检证实为巨细胞修复性肉芽肿。血液检测显示甲状旁腺激素水平非常高，怀疑是原发性甲状旁腺功能亢进导致的棕色瘤。手术切除异位腺瘤使内分泌状况得到纠正。
据我们所知，这是首例因异位甲状旁腺腺瘤导致面部骨骼多发性棕色瘤的报道病例。文中描述了诊断陷阱和治疗挑战。
