拉米夫定与替诺福韦联合治疗HIV-1与野生型乙型肝炎病毒合并感染患者的96周疗效
Ninety-six-week efficacy of combination therapy with lamivudine and tenofovir in patients coinfected with HIV-1 and wild-type hepatitis B virus.
作者信息
Bani-Sadr F, Palmer P, Scieux C, Molina J M
机构信息
Service des Maladies Infectieuses et Tropicales, Hôpital Saint Louis, Paris, France.
出版信息
Clin Infect Dis. 2004 Oct 1;39(7):1062-4. doi: 10.1086/424012. Epub 2004 Sep 13.
We describe 6 patients who were coinfected with human immunodeficiency virus (HIV) type 1 and wild-type hepatitis B virus (HBV), in whom complete and sustained antiviral activity against wild-type HBV strains was attained during 96 weeks of combination therapy with lamivudine and tenofovir. The use of combination therapy with lamivudine and tenofovir for the treatment of HBV infection is very promising in the treatment of HIV/HBV coinfection.
我们描述了6例同时感染1型人类免疫缺陷病毒（HIV）和野生型乙型肝炎病毒（HBV）的患者，在接受拉米夫定和替诺福韦联合治疗的96周期间，他们对野生型HBV毒株实现了完全且持续的抗病毒活性。拉米夫定和替诺福韦联合疗法用于治疗HBV感染，在HIV/HBV合并感染的治疗中非常有前景。
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