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使用Technolas 217准分子激光对LASEK治疗近视和近视散光的疗效、可预测性及安全性进行分析。

Analysis of the efficacy, predictability, and safety of LASEK for myopia and myopic astigmatism using the Technolas 217 excimer laser.

作者信息

Partal Andreea E, Rojas Maria C, Manche Edward E

机构信息

Stanford University School of Medicine, Stanford, CA 94305, USA.

出版信息

J Cataract Refract Surg. 2004 Oct;30(10):2138-44. doi: 10.1016/j.jcrs.2004.02.083.

Abstract

PURPOSE

To evaluate the efficacy, predictability, and safety of laser-assisted subepithelial keratectomy (LASEK) for the treatment of myopia and myopic astigmatism.

SETTING

Stanford University Eye Laser Center, Stanford, California, USA.

METHODS

This retrospective analysis comprised 102 eyes that had LASEK for myopia using the Bausch & Lomb Technolas 217 excimer laser. Primary outcome variables including uncorrected visual acuity (UCVA), best spectacle- corrected visual acuity (BSCVA), manifest refraction, and complications were evaluated at 3, 6, and 12 months. Vector analysis was performed on eyes that received astigmatic correction.

RESULTS

The mean spherical equivalent was -7.03 diopters (D) +/- 2.61 (SD) preoperatively, +0.19 +/- 0.64 D at 3 months, +0.23 +/- 0.82 D at 6 months, and +0.03 +/- 0.63 D at 12 months (P<.001). At 3, 6, and 12 months, the UCVA was 20/20 or better in 66%, 67%, and 83% of eyes, respectively, and 20/40 or better in 98%, 99%, and 100%; 74%, 70%, and 83%, respectively, were within +/-0.5 D of emmetropia, and 89%, 86%, and 97%, respectively, were within +/-1.0 D. No eye lost more than 2 lines of BSCVA. At 3, 6, and 12 months, 10.0%, 8.7%, and 0% of eyes, respectively, had trace corneal haze. Vector analysis found a success rate of approximately 78% to 80% in achieving the astigmatic surgical correction at the 3 postoperative visits.

CONCLUSIONS

Laser-assisted subepithelial keratectomy was an effective, predictable, and safe procedure for the treatment of myopia and myopic astigmatism. Further studies are needed to determine the role of LASEK in the refractive surgery spectrum.

摘要

目的

评估准分子激光上皮下角膜磨镶术(LASEK)治疗近视及近视散光的疗效、可预测性和安全性。

地点

美国加利福尼亚州斯坦福大学眼科激光中心。

方法

本回顾性分析纳入了102只接受使用博士伦Technolas 217准分子激光进行LASEK治疗近视的眼睛。在3个月、6个月和12个月时评估主要结局变量,包括裸眼视力(UCVA)、最佳矫正视力(BSCVA)、显验光和并发症。对接受散光矫正的眼睛进行矢量分析。

结果

术前平均等效球镜度为-7.03屈光度(D)±2.61(标准差),3个月时为+0.19±0.64 D,6个月时为+0.23±0.82 D,12个月时为+0.03±0.63 D(P<0.001)。在3个月、6个月和12个月时,分别有66%、67%和83%的眼睛UCVA达到20/20或更好,98%、99%和100%的眼睛达到20/40或更好;分别有74%、70%和83%的眼睛屈光不正度数在正视眼±0.5 D范围内,89%、86%和97%的眼睛在±1.0 D范围内。没有眼睛的BSCVA下降超过2行。在3个月、6个月和12个月时,分别有10.0%、8.7%和0%的眼睛有微量角膜 haze。矢量分析发现在术后3次随访中实现散光手术矫正的成功率约为78%至80%。

结论

准分子激光上皮下角膜磨镶术是治疗近视及近视散光的一种有效、可预测且安全的手术方法。需要进一步研究以确定LASEK在屈光手术领域中的作用。

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