Bocio Ana, Domingo Jose L
Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, 43201 Reus, Spain.
Environ Res. 2005 Jan;97(1):1-9. doi: 10.1016/j.envres.2004.01.012.
Concentrations of polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) were measured in foodstuffs randomly acquired in various locations of Tarragona County (Catalonia, Spain) in September 2002. A total of 36 composite samples, belonging to various food groups (vegetables, fruits, meat and meat products, fish and seafood, cereals, pulses, milk, dairy products, eggs, and oils and fats) were analyzed by high-resolution gas chromatography/high-resolution mass spectrometry. The dietary intake of PCDD/Fs was subsequently determined. For calculations, recent data on consumption of the selected food items were used. Total dietary intake of PCDD/Fs for the general population of Tarragona County was estimated to be 59.6 pg I-TEQ/day (63.8 pg WHO-TEQ/day). Fish and seafood (33.7%), oils and fats (15.3%), cereals (14.4%), and dairy products (13.7%) were the most important contributors to this intake. This PCDD/F intake is notably lower than the intake estimated in 1998 for the same geographical area, 210.1 pg I-TEQ/day. The current PCDD/F dietary intake is below the tolerable intake range of 1-4 pg TEQ/kg body weight/day established by the WHO in 1998. Finally, the current intake is compared with the dietary intakes of PCDD/Fs recently (2001-2003) reported for a number of regions and countries.
2002年9月,对在西班牙加泰罗尼亚塔拉戈纳县不同地点随机采集的食品中的多氯代二苯并 - 对 - 二噁英(PCDD)和多氯代二苯并呋喃(PCDF)浓度进行了测定。通过高分辨率气相色谱/高分辨率质谱法分析了总共36个属于不同食品组(蔬菜、水果、肉类及肉制品、鱼类和海鲜、谷物、豆类、牛奶、乳制品、蛋类以及油脂)的混合样本。随后测定了PCDD/Fs的膳食摄入量。计算时使用了所选食品近期的消费数据。塔拉戈纳县普通人群PCDD/Fs的总膳食摄入量估计为59.6皮克国际毒性当量/天(63.8皮克世界卫生组织毒性当量/天)。鱼类和海鲜(33.7%)、油脂(15.3%)、谷物(%)和乳制品(13.7%)是这一摄入量的最重要贡献来源。这一PCDD/F摄入量明显低于1998年对同一地理区域估计的摄入量,即210.1皮克国际毒性当量/天。目前PCDD/F的膳食摄入量低于世界卫生组织1998年确定的1 - 4皮克毒性当量/千克体重/天的可耐受摄入量范围。最后,将当前摄入量与近期(2001 - 2003年)多个地区和国家报告的PCDD/Fs膳食摄入量进行了比较。 (原文中谷物贡献率数据缺失,译文已注明)