Llobet Juan M, Martí-Cid Roser, Castell Victoria, Domingo José L
GRET-CERETOX, School of Pharmacy, University of Barcelona, Avgda. Joan XXIII s/n, 08028 Barcelona, Spain.
Toxicol Lett. 2008 May 5;178(2):117-26. doi: 10.1016/j.toxlet.2008.02.012. Epub 2008 Mar 18.
The concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDFs), and 18 polychlorinated biphenyls (PCBs) were determined in samples of foodstuffs widely consumed by the population of Catalonia, Spain. The dietary intake of PCDD/PCDFs and dioxin-like (DL)-PCBs was subsequently estimated for the population of this Spanish region. These results were compared with those of a previous survey performed during 2000. For PCDD/PCDFs, the highest WHO-TEQ values corresponded to oils and fats (0.223 ng/kg), followed by fish and seafood (0.131 ng/kg) and dairy products (0.057 ng/kg), while the lowest levels were found in fruits (0.003 ng/kg), as well as in vegetables and milk (0.009 ng/kg). For DL-PCBs the highest WHO-TEQ values corresponded to the groups of fish and seafood (0.761 ng/kg) followed by oils and fats (0.169 ng/kg), and dairy products (0.039 ng/kg), while the lowest values were observed in fruits (0.004 ng/kg), and vegetables (0.005 ng/kg) and tubers (0.006 ng/kg). The current dietary intakes of PCDD/PCDFs, DL-PCBs, and PCDD/PCDFs plus DL-PCBs were estimated to be 25.7, 52.4, and 78.1 pg WHO-TEQ/day vs. 95.4, 150.1, and 245.5 pg WHO-TEQ/day found in our previous survey. It means reductions of 73%, 65%, and 68%, for PCDD/PCDFs, DL-PCBs, and PCDD/PCDFs plus DL-PCBs, respectively. The current estimated intake for an adult male, 1.12 pg WHO-TEQ/kg body weight per day, is lower than most intakes recently reported in a number of countries over the world.
测定了西班牙加泰罗尼亚地区居民广泛食用的各类食品样本中多氯二苯并 - 对 - 二恶英和多氯二苯并呋喃（PCDD/PCDFs）以及18种多氯联苯（PCBs）的浓度。随后估算了该西班牙地区居民PCDD/PCDFs和类二恶英（DL）-PCBs的膳食摄入量。将这些结果与2000年进行的一项前期调查结果进行了比较。对于PCDD/PCDFs，世界卫生组织毒性当量（WHO-TEQ）最高值出现在油脂类（0.223 ng/kg），其次是鱼类和海鲜类（0.131 ng/kg）以及乳制品（0.057 ng/kg），而水果类（0.003 ng/kg）以及蔬菜和牛奶类（0.009 ng/kg）中的含量最低。对于DL-PCBs，WHO-TEQ最高值出现在鱼类和海鲜类（0.761 ng/kg），其次是油脂类（0.169 ng/kg）以及乳制品（0.039 ng/kg），而水果类（0.004 ng/kg）、蔬菜类（0.005 ng/kg）和块茎类（0.服务条款006 ng/kg）中的含量最低。目前PCDD/PCDFs、DL-PCBs以及PCDD/PCDFs加DL-PCBs的膳食摄入量估计分别为25.7、52.4和78.1 pg WHO-TEQ/天，而我们前期调查中的数值分别为95.4、150.1和245.5 pg WHO-TEQ/天。这意味着PCDD/PCDFs、DL-PCBs以及PCDD/PCDFs加DL-PCBs的摄入量分别减少了73%、65%和68%。目前成年男性的估计摄入量为每天1.12 pg WHO-TEQ/千克体重，低于世界上许多国家最近报告的大多数摄入量。
