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经皮丁丙诺啡治疗癌症相关疼痛：三例报告。

Treatment of cancer-related pain with transdermal buprenorphine: a report of three cases.

作者信息

Schriek Paul

机构信息

Twachtmannshof 4, 29229, Celle, Germany.

出版信息

Support Care Cancer. 2004 Dec;12(12):882-4. doi: 10.1007/s00520-004-0695-1. Epub 2004 Oct 9.

DOI:10.1007/s00520-004-0695-1
PMID:15480815
Abstract

Three patients suffering from pain arising from renal and metastasing prostate and breast cancer were successfully treated with transdermal buprenorphine. The three cases demonstrate that transdermal buprenorphine is an easy-to-use and effective therapeutic option for the treatment of advanced cancer pain, that it can also be used in opioid rotation as an alternative after formerly applied steps II or III opioids have failed and that long-term treatment without dose escalation or compromise in tolerability is possible.

摘要

三名患有由肾癌以及转移性前列腺癌和乳腺癌引起疼痛的患者通过透皮丁丙诺啡治疗获得成功。这三例病例表明，透皮丁丙诺啡是治疗晚期癌痛的一种易于使用且有效的治疗选择，在先前应用的第二或第三阶梯阿片类药物治疗失败后，它也可作为替代药物用于阿片类药物轮换，并且可以进行长期治疗而无需增加剂量或降低耐受性。

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Treatment of cancer-related pain with transdermal buprenorphine: a report of three cases.经皮丁丙诺啡治疗癌症相关疼痛：三例报告。
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2
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引用本文的文献

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Toward a systematic approach to opioid rotation.朝向一种阿片类药物转换的系统方法。
J Pain Res. 2014 Oct 17;7:589-608. doi: 10.2147/JPR.S55782. eCollection 2014.
2
Transdermal buprenorphine in the management of persistent pain - safety aspects.经皮丁丙诺啡治疗持续性疼痛的安全性方面。
Ther Clin Risk Manag. 2006 Mar;2(1):115-25.
3
Is there a ceiling effect of transdermal buprenorphine? Preliminary data in cancer patients.透皮丁丙诺啡是否存在天花板效应？癌症患者的初步数据。

本文引用的文献

1
Old dog--new (ma)trix.老狗——新（基质）。 （注：这里的“(ma)trix”不太明确准确含义，可能是特定语境下的术语，根据字面翻译如此。）
Br J Anaesth. 2003 Jun;90(6):722-4. doi: 10.1093/bja/aeg133.
2
Buprenorphine TDS: the clinical development rationale and results.丁丙诺啡透皮贴剂：临床研发原理与结果
Int J Clin Pract Suppl. 2003 Feb(133):15-8; discussion 23-4.
3
Buprenorphine and the transdermal system: the ideal match in pain management.丁丙诺啡与透皮给药系统：疼痛管理的理想组合。
Support Care Cancer. 2007 Apr;15(4):441-4. doi: 10.1007/s00520-006-0169-8. Epub 2006 Nov 15.
4
Buprenorphine in cancer pain.丁丙诺啡用于癌症疼痛
Support Care Cancer. 2005 Nov;13(11):878-87. doi: 10.1007/s00520-005-0849-9. Epub 2005 Jul 12.
Int J Clin Pract Suppl. 2003 Feb(133):9-14; discussion 23-4.
4
Analgesic efficacy and tolerability of transdermal buprenorphine in patients with inadequately controlled chronic pain related to cancer and other disorders: a multicenter, randomized, double-blind, placebo-controlled trial.经皮丁丙诺啡对癌症及其他疾病相关慢性疼痛控制不佳患者的镇痛疗效和耐受性：一项多中心、随机、双盲、安慰剂对照试验
Clin Ther. 2003 Jan;25(1):150-68. doi: 10.1016/s0149-2918(03)90019-1.
5
Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients.透皮芬太尼用于癌症疼痛的管理：对1005例患者的调查。
Palliat Med. 2001 Jul;15(4):309-21. doi: 10.1191/026921601678320296.
6
Buprenorphine in a transdermal therapeutic system--a new option.经皮治疗系统中的丁丙诺啡——一种新选择。
Clin Rheumatol. 2002 Feb;21 Suppl 1:S13-6. doi: 10.1007/s100670200031.
7
Treatment of cancer pain with transdermal fentanyl.透皮芬太尼治疗癌痛
Lancet Oncol. 2001 Mar;2(3):165-72. doi: 10.1016/S1470-2045(00)00258-8.
8
Validation of World Health Organization Guidelines for cancer pain relief: a 10-year prospective study.世界卫生组织癌症疼痛缓解指南的验证：一项为期10年的前瞻性研究。
Pain. 1995 Oct;63(1):65-76. doi: 10.1016/0304-3959(95)00017-M.
9
Buprenorphine: a review of its pharmacological properties and therapeutic efficacy.丁丙诺啡：其药理特性与治疗效果综述
Drugs. 1979 Feb;17(2):81-110. doi: 10.2165/00003495-197917020-00001.