Motoyama Osamu, Muto Atsuhiko, Ogiwara Hidetaka, Mizuiri Sonoo, Kawamura Sadao, Iitaka Kikuo
First Department of Pediatrics, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo 143-8541, Japan.
Clin Exp Nephrol. 2004 Sep;8(3):263-5. doi: 10.1007/s10157-004-0279-x.
An obese male patient with steroid-dependent nephrotic syndrome since age 6 years had a thirty-third relapse at the age of 29 years. Renal biopsy showed focal segmental glomerulosclerosis. Proteinuria disappeared after treatment with prednisolone. He went into complete remission and renal function remained normal at the age of 31 years. Focal segmental glomerulosclerosis associated with obesity was suspected. Long-term follow-up with renal biopsy is necessary in obese children with steroid-dependent nephrotic syndrome.
一名自6岁起就患有类固醇依赖型肾病综合征的肥胖男性患者，在29岁时出现了第33次复发。肾活检显示局灶节段性肾小球硬化。使用泼尼松龙治疗后蛋白尿消失。他完全缓解，31岁时肾功能仍保持正常。怀疑与肥胖相关的局灶节段性肾小球硬化。对于患有类固醇依赖型肾病综合征的肥胖儿童，有必要进行长期肾活检随访。
