Trainin E B, Gomez-Leon G
Int J Pediatr Nephrol. 1982 Jun;3(2):55-8.
In this report, we describe the case of a boy who developed the nephrotic syndrome at one and one-half years of age, remained steroid-responsive for nine years, but then became steroid-resistant, associated with the development of progressive glomerular sclerosis and renal insufficiency. We suggest that this evolution is evidence in favor of the view that minimal change disease and focal glomerulosclerosis have a common pathogenesis.
在本报告中，我们描述了一名1岁半时患肾病综合征的男孩的病例。该男孩对类固醇治疗敏感长达9年，但随后转为类固醇抵抗，并伴有进行性肾小球硬化和肾功能不全。我们认为，这种病情演变支持微小病变病和局灶节段性肾小球硬化具有共同发病机制这一观点。
